Results 61 to 70 of about 215,554 (316)
Advances in Materials Science and Engineering, 2022 A numerical coupling approach is proposed to fast predict the acoustic radiation from a vibrating large-complicated underwater structure. In this study, the physical mechanism of sound radiation from underwater large target is used for the first time to ...
Yongzhuang Tang +3 more
doaj +1 more source
Subregion Boundary Element Method
JSME international journal. Ser. A, Mechanics and material engineering, 1993 The system of equations for each subregion, which is derived from the boundary integral equation, is transformed to an equation similar to the stiffness equation of the finite element method. The global equation is made by the superposition of these matrix equations.
Kita, Eisuke, Kamiya, Norio
openaire +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Wavelet formulation of the polarizable continuum model. II. Use of piecewise bilinear boundary elements [PDF]
, 2015 The simplicity of dielectric continuum models has made them a standard tool in almost any Quantum Chemistry (QC) package. Despite being intuitive from a physical point of view, the actual electrostatic problem at the cavity boundary is challenging: the ...
Simen Sommerfelt Reine +12 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Electronic Journal of Structural Engineering, 2012 In the present paper, a direct time domain procedure is used for dynamic linear and nonlinear analysis of the coupled system of reservoir-dam-foundation in 3D space.
H. Mirzabozorg +2 more
doaj +1 more source
Scientific Reports, 2021 The autonomy of segment-specific regulatory domains in the Bithorax complex is conferred by boundary elements and associated Polycomb response elements (PREs). The Fab-6 boundary is located at the junction of the iab-5 and iab-6 domains. Previous studies
Nikolay Postika +3 more
doaj +1 more source
A boundary element method for a class of elliptic boundary value problems of functionally graded media [PDF]
, 2017 A Boundary Element Method (BEM) is derived for obtaining solutions to a class of elliptic boundary value prob- lems (BVPs) of functionally graded media (FGM).
Haddade, A. +11 more
core +1 more source