Results 71 to 80 of about 215,554 (316)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Effect of the surface-active elements on grain boundary oxidation of hot-stamped steel
Materials Letters: XThe effects of minor surface-active alloy elements Sb and Sn on hot-stamped steel grain boundary oxidation at different coiling temperatures were studied through tube sealing and soaking.
Y.Y. Ge, Q.L. Cui
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Energies, 2018 Numerical simulation is widely used in the field of computational building physics for the definition of the thermal performance of building elements. An integral component of numerical simulation using finite elements is the boundary conditions, which ...
Paris A. Fokaides +2 more
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Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity. [PDF]
PLoS Genetics, 2011 Genomic maps of chromatin modifications have provided evidence for the partitioning of genomes into domains of distinct chromatin states, which assist coordinated gene regulation.
Meiji Kit-Wan Ma +3 more
doaj +1 more source
The Boundary Element Method in elastodynamics
, 1982 As is well known B.E.M. is obtained as a mixture of the integral representation formula of classical elasticity and the discretization philosophy of the finite element method (F.E.M.). The paper presents the application of B.E.M. to elastodynamic problems.
Dominguez Abascal, José +1 more
openaire +4 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Rudarsko-geološko-naftni Zbornik, 1993 This paper includes main theses, proofs, and procedures of Boundary Element Method (BEM). The computer program. announced in 1981, for the calculation of stresses and strains around underground opening was used, comprising plane strain state for elastic ...
Mladen Hudec, Lidija Frgić
doaj
Metals, 2019 Hydrogen enhanced decohesion is expected to play a major role in ferritic steels, especially at grain boundaries. Here, we address the effects of some common alloying elements C, V, Cr, and Mn on the H segregation behaviour and the decohesion mechanism ...
Aparna P. A. Subramanyam +4 more
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Interfacing Finite Element and Boundary Element Discretizations
Applied Mathematical Modelling, 1981 This paper reviews critically various implementation methods for coupling a mechanical finite element model to an infinite external acoustic domain discretized through boundary-element techniques. The associated physical problem is that of a three-dimensional structure submerged in an acoustic fluid, and impinged by a pressure shock wave.
openaire +2 more sources