Results 71 to 80 of about 4,570,639 (247)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Engineering Analysis with Boundary Elements
This journal is specifically dedicated to the dissemination of the latest developments of new engineering analysis techniques using boundary elements and other mesh reduction methods.
Ballestra Luca Vincenzo
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
上海师范大学学报. 自然科学版, 2017 The hydrogenation-disproportionation-desorption-recombination (HDDR) process is the main technique for the fabrication of anisotropic NdFeB magnetic powder.But the intrinsic coercivity (HC) of HDDR magnetic powder is low.The addition of heavy rare earth ...
Lyu Meng +5 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
, 2013 Recently, sinh transformations have been proposed to evaluate nearly weakly singular integrals which arise in the boundary element method. These transformations have been applied to the evaluation of nearly weakly singular integrals arising in the ...
Johnston, Barbara M +2 more
core +1 more source
A boundary element method for a class of elliptic boundary value problems of functionally graded media [PDF]
, 2017 A Boundary Element Method (BEM) is derived for obtaining solutions to a class of elliptic boundary value prob- lems (BVPs) of functionally graded media (FGM).
Haddade, A. +11 more
core +1 more source
An efficient implementation of the boundary integral equation method in elastoplastic stress analysis of frictional contact problems [PDF]
, 1999 21st International Conference on the Boundary Element Method -- AUG, 1999 -- OXFORD UNIV, WORCESTER COLL, OXFORD, ENGLANDFor two-dimensional elastoplastic stress analysis of frictional contact problems, an isoparametric quadratic formulation of the ...
Gun, H
core +1 more source