Results 51 to 60 of about 454,024 (311)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Journal of Fluid Science and Technology, 2011 Spatial direct numerical simulation results are presented for transitional/turbulent supersonic isothermal flat plate boundary layers at M = 2.0 and impinging shock wave-boundary layer interactions.
Yusuke TOKURA, Hiroshi MAEKWA
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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A Study on the Separation Length of Shock Wave/Turbulent Boundary Layer Interaction
International Journal of Aerospace Engineering, 2019 The separation length of shock wave/boundary layer interaction (SWBLI) was studied by a numerical method, which was validated by experimental results. The computational domain was two-dimensional (2-D).
Yong-yi Zhou, Yi-long Zhao, Yu-xin Zhao
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Effects of Surface Roughness on the Flow of High-Lift Low-Pressure Turbine
Journal of Harbin University of Science and Technology, 2019 In order to get the effects of surface roughness on turbine profile loss in different working conditions, the flow of a frontloaded blade at different incidences and different Reynolds number was analyzed in detail by numerical simulation The results ...
ZHANG Zong-chen, QIAO Wei-yang, BAI Tao
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Eliminating Boundary Layer Separation on a Cylinder with Nonuniform Suction
International Journal of Aerospace Engineering, 2020 Boundary layer separation negatively influences the performance of aerospace vehicles, for example, by triggering static stall or reducing combustion engine efficiency.
James Ramsay +2 more
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ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Numerical Investigation of Jet Angle Effect on Airfoil Stall Control
Applied Sciences, 2019 Numerical study on flow separation control is conducted for a stalled airfoil with steady-blowing jet. Stall conditions relevant to a rotorcraft are of interest here.
Junkyu Kim +6 more
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AIP Advances, 2022 The three-dimensional (3D) interactions between crossing shock waves and a turbulent boundary layer (CSWBLI) inside a symmetric double fin are experimentally studied using nanoparticle-based planar laser scattering, supersonic particle image velocimetry,
Lican Wang +5 more
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Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source