Results 101 to 110 of about 1,508,431 (314)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

AABP Association and Conference News

, 2007
Description and highlights of the the Annual Conference of the American Association of Bovine Practitioners (39th : 2006), officers, district news, events, awards, and other ...
American Association of Bovine Practione
core   +1 more source

Study on Milk Production Dynamics and Major Chemical Milk Components in Brown Sire Dams of Brown Swiss-Type from the Research and Development Station for Bovine Raising - Arad

Scientific Papers Animal Science and Biotechnologies, 2023
The present work was carried out to determine the influence of lactation rank on the milk yield, fat and protein evolution. Observations were carried out on 117 lactations, as follows: 15 first lactations, 22 second lactations, 26 third lactations, 28 ...
Florin Cristian Neciu, Ludovic-Toma Cziszter, Radu Ionel Neamț, Daniela Elena Ilie, Florin Corneliu Marinescu   +4 more
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

AABP Conference (2012): Executive Vice President’s Report

, 2013
Description of the 45th American Association of Bovine Practitioners Conference ...
Bovine Practitioners, American Association of
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

AABP Conference (2012): AABP Gateway Gala and Dinner

, 2013
Description of the 45th American Association of Bovine Practitioners Conference ...
Bovine Practitioners, American Association of
core   +1 more source

Assessment of BoAHV-1 Seronegative Latent Carrier by the Administration of Two Infectious Bovine Rhinotracheitis Live Marker Vaccines in Calves

Vaccines
Seronegative latent carriers (SNLCs) are animals that carry the virus without detectable antibodies and pose a risk for disease transmission and diagnostic challenges, suggesting the importance of consideration of marker vaccines in managing them ...
Stefano Petrini, Cecilia Righi, Giulia Costantino, Eleonora Scoccia, Paola Gobbi, Claudia Pellegrini, Michela Pela, Monica Giammarioli, Giulio Viola, Roberto Sabato, Elena Tinelli, Francesco Feliziani   +11 more
doaj   +1 more source

BOVINE TUBERCULOSIS. [PDF]

The Lancet, 1892
n ...
openaire   +1 more source