Results 51 to 60 of about 1,408,621 (315)

Demonstration of early functional compromise of bone marrow derived hematopoietic progenitor cells during bovine neonatal pancytopenia through in vitro culture of bone marrow biopsies [PDF]

, 2012
Background Bovine neonatal pancytopenia (BNP) is a syndrome characterised by thrombocytopenia associated with marked bone marrow destruction in calves, widely reported since 2007 in several European countries and since 2011 in New Zealand. The disease is
Melzi Eleonora, Bell Charlotte R, Bell, Charlotte, Charlotte R Bell, Keith T Ballingall, Kim Willoughby, Scholes, Sandra F E, Dagleish, Mark P, Rocchi Mara S, Ballingall Keith T, Laming, Eleanor, Scholes Sandra FE, Laming Eleanor, Rocchi, Mara S, Maira Connelly, Melzi, Eleonora, Connelly Maira, Willoughby Kim, Ballingall, Keith T, Connelly, Maira, Dagleish Mark P, Eleanor Laming, Eleonora Melzi, Mark P Dagleish, Mara S Rocchi, Willoughby, Kim, Sandra FE Scholes   +26 more
core   +1 more source

A draft genome of Drung cattle reveals clues to its chromosomal fusion and environmental adaptation

Communications Biology, 2022
Integrated genomic, transcriptomic, and methylomic data from the endangered Drung cattle (Bos frontalis) provide further insight into its unique physiology and adaptation to alpine environments.
Yan Chen, Tianliu Zhang, Ming Xian, Rui Zhang, Weifei Yang, Baqi Su, Guoqiang Yang, Limin Sun, Wenkun Xu, Shangzhong Xu, Huijiang Gao, Lingyang Xu, Xue Gao, Junya Li   +13 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Produktiver erster nationaler BovINE-Workshop am 12. November 2020: [Tagungsbericht] [PDF]

, 2020
Am 12.11.2020 fand der erste nationale BovINE-Workshop als Online-Veranstaltung statt. Der Workshop war mit 33 Teilnehmern gut besucht. Neben Landwirten und Vertretern verschiedener Zuchtorganisationen nahmen auch Industrie und die Fachpresse an der ...

core  

Genomic Prediction Using LD-Based Haplotypes Inferred From High-Density Chip and Imputed Sequence Variants in Chinese Simmental Beef Cattle

Frontiers in Genetics, 2021
A haplotype is defined as a combination of alleles at adjacent loci belonging to the same chromosome that can be transmitted as a unit. In this study, we used both the Illumina BovineHD chip (HD chip) and imputed whole-genome sequence (WGS) data to ...
Hongwei Li, Bo Zhu, Bo Zhu, Ling Xu, Zezhao Wang, Lei Xu, Peinuo Zhou, Han Gao, Peng Guo, Yan Chen, Xue Gao, Lupei Zhang, Huijiang Gao, Huijiang Gao, Wentao Cai, Lingyang Xu, Junya Li, Junya Li   +17 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Evaluation of Passive Immunity Induced by Immunisation Using Two Inactivated gE-deleted Marker Vaccines against Infectious Bovine Rhinotracheitis (IBR) in Calves

Vaccines, 2020
Different types of vaccines against Infectious Bovine Rhinotracheitis (IBR) are commercially available. Among these, inactivated glycoprotein E (gE)-deleted marker vaccines are commonly used, but their ability to induce passive immunity is poorly known ...
Stefano Petrini, Cecilia Righi, Carmen Iscaro, Giulio Viola, Paola Gobbi, Eleonora Scoccia, Elisabetta Rossi, Claudia Pellegrini, Gian Mario De Mia   +8 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Validation of a Commercial Indirect ELISA Kit for the Detection of Bovine alphaherpesvirus1 (BoHV-1)-Specific Glycoprotein E Antibodies in Bulk Milk Samples of Dairy Cows

Veterinary Sciences, 2022
In this study, we validated a commercial indirect enzyme-linked immunosorbent assay (ELISA) to detect antibodies to glycoprotein E (gE) of Bovine alphaherpesvirus 1 (BoHV-1) in bulk milk (BM) samples using the OIE Manual of Diagnostic Tests and Vaccines ...
Cecilia Righi, Carmen Iscaro, Laura Ferroni, Sergio Rosati, Claudia Pellegrini, Chiara Nogarol, Elisabetta Rossi, Annalisa Dettori, Francesco Feliziani, Stefano Petrini   +9 more
doaj   +1 more source