Identification of BoLA Alleles Associated with BLV Proviral Load in US Beef Cows
Bovine leukemia virus (BLV) causes enzootic bovine leukosis, the most common neoplastic disease in cattle. Previous work estimates that 78% of US beef operations and 38% of US beef cattle are seropositive for BLV.
Ciarra H. LaHuis +7 more
doaj +1 more source
Enzootic bovine leukosis (EBL) is characterized by the development of tumors of lymphatic tissues (lymphosarcoma), such as the thymus, spleen and lymph nodes.
Floss, Jeanette L. +1 more
core
Bovine leukemia virus can be classified into seven genotypes: evidence for the existence of two novel clades. [PDF]
Previous studies have classified the env sequences of bovine leukemia virus (BLV) provirus from different locations worldwide into between two and four genetic groupings. These different studies gave unique names to the identified groups and no study has
Campos, Rodolfo H. +4 more
core +2 more sources
BLV-CoCoMo-qPCR-3: Improved BLV-CoCoMo-qPCR for Bovine Leukemia Virus Detection by Mixing Probes Targeting all BLV Variants [PDF]
Abstract Background: The bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis, the most common neoplastic disease in cattle. The proviral load (PVL) is an important index for estimating disease progression. Previously, we developed a quantitative real-time PCR (qPCR) assay to measure the PVL of BLV using coordination ...
Liushiqi Borjigin +12 more
openaire +1 more source
Abstract Background Enzootic bovine leukosis (EBL), caused by the bovine leukaemia virus (BLV), has exhibited increasing infection rates in Japan. While many farms implement various infection prevention measures, practical challenges—such as barn structure and availability of replacement cattle—can hinder farm purification efforts.
Chikako Tani +4 more
wiley +1 more source
The cattle industry is suffering economic losses caused by bovine leukemia virus (BLV) and enzootic bovine leukosis (EBL), the clinical condition associated with BLV infection.
Kosuke Notsu +7 more
doaj +1 more source
Using shared needles for subcutaneous inoculation can transmit bluetongue virus mechanically between ruminant hosts [PDF]
Bluetongue virus (BTV) is an economically important arbovirus of ruminants that is transmitted by Culicoides spp. biting midges. BTV infection of ruminants results in a high viraemia, suggesting that repeated sharing of needles between animals could ...
A Tarantola +39 more
core +4 more sources
Stable infection of a bovine mammary epithelial cell line (MAC-T) with bovine leukemia virus (BLV) [PDF]
Bovine leukemia virus (BLV) is a retrovirus that affects cattle causing a lymphoproliferative disease. BLV infection has been associated with misbalance of the immune response causing a higher incidence of other infections. Mastitis is one of the most important conditions that affect milk production in cattle. The aim of this study was to stably infect
Lucia Martinez Cuesta +6 more
openaire +3 more sources
CRISPR‐driven diagnostics: Molecular mechanisms, clinical efficacy and translational challenges
The CRISPR/Cas system has emerged as a transformative tool in the field of molecular diagnosis, offering unprecedented sensitivity, specificity and rapid detection capabilities. This review further examines the molecular mechanisms of CRISPR tools, compares their clinical efficacy with traditional methods and highlights cutting‐edge innovations such as
Zilong Wang +7 more
wiley +1 more source
Homologies entre les deux rétrovirus BLV et HTLV-1 et développement d’une nouvelle approche thérapeutique basée sur la levée de la latence virale [PDF]
Homologies between BLV and HTLV-1 retroviruses and development of a novel therapeutic approach based on induction of viral expression. BLV (bovine leukemia virus) and HTLV-1 (human T-cell leukemia virus) are related retroviruses inducing leukemia (BLV ...
Nicolas Gillet +2 more
doaj

