Results 71 to 80 of about 7,611 (214)

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Evaluation of diagnostic techniques for the detection of \ud Bovine Viral Diarrhoea Virus (BVDV) in infected and persistently infected cattle\ud [PDF]

, 2009
Bovine Viral Diarrhoea Virus (BVDV) is a significant pathogen associated with gastrointestinal, respiratory, and reproductive diseases of cattle worldwide.
Romero Tejeda, Aurora
core  

Prevalence of bovine respiratory viruses in cattle calves in Kangra district of Himachal Pradesh

Indian Journal of Animal Sciences
Respiratory diseases causing pneumonia are the 2nd leading cause of mortality in bovine calves and are primarily caused by viral pathogens. The present study was undertaken in cattle calves under twelve months of age for detecting four respiratory ...
RAHUL SINGH, RAJENDRA DAMU PATIL, PRIYANKA, RAKESH KUMAR, RAJESH KUMAR ASRANI, VIPAN KUMAR GUPTA   +5 more
doaj   +1 more source

Molecular analysis of bovine viral diarrhoea virus isolates from South Africa

Onderstepoort Journal of Veterinary Research, 2003
The presence of bovine viral diarrhoea virus in South Africa has been confirmed by several serological surveys. However, little is known about its biological properties.
N. Kabongo, C. Baule, M. Van Vuuren
doaj   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

Epidemiological Investigation and Phylogenetic Analysis of Bovine Respiratory Disease Complex in Northern China

Veterinary Medicine and Science
Bovine respiratory disease complex (BRDC), a multifactorial syndrome driven by viral and bacterial co‐infections, poses significant challenges to cattle health in northern China.
Yaping Zhou, Ting Guo, Hongmei Zhao, Yongqing Hao   +3 more
doaj   +1 more source

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, EarlyView.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

An outbreak of abortions, stillbirths and malformations in a Spanish sheep flock associated with a bovine viral diarrhoea virus 2-contaminated orf vaccine.

, 2021
Bovine viral diarrhoea virus (BVDV) is a pestivirus that affects both cattle and sheep, causing an array of clinical signs, which include abortions and malformations in the offspring. Manufacturing of modified live virus (MLV) vaccines often includes the
Asín, Javier, de Miguel, Ricardo, Schweizer, Matthias, Akerman, Alberto, Schweizer, Matthias; https://orcid.org/, Stalder, Hanspeter, Luján, Lluís, Rodríguez‐Largo, Ana, Luján, Lluís; https://orcid.org/, Hilbe, Monika, Rodríguez-Largo, Ana, Lanau, Antonio   +11 more
core   +1 more source

Genotyping of bovine viral diarrhoea virus isolates from the Czech Republic

Veterinární Medicína, 2009
This study was focused on the genetic typing of bovine viral diarrhoea virus (BVDV) isolates obtained from 41 serum samples of persistently infected cattle in the Czech Republic in the period of 2004 to 2007. For the differentiation of BVDV isolates, the
B. Robesova, K. Kovarcik, S. Vilcek
doaj   +1 more source

An assessment of bovine herpes virus 4 as a causative agent in abortions and neonatal death

Onderstepoort Journal of Veterinary Research, 2020
Numerous viruses, including bovine viral diarrhoea virus (BVDV), bovine herpes virus 1 (BoHV-1) and bovine herpes virus 4 (BoHV-4), and other pathogens are the most common causes of reproductive disorders and are responsible for huge economic losses in ...
Seval B. Dağalp, Ali R. Babaoglu, Firat Doğan, Touraj A. Farzani, Feray Alkan   +4 more
doaj   +1 more source