Results 81 to 90 of about 1,590,845 (193)

SAT1‐Induced Spermidine Depletion Potentiates Food Allergy

Advanced Science, EarlyView.
Spermidine depletion, driven by upregulated spermidine/spermine N1‐acetyltransferase (SAT1), potentiates food allergy by promoting mast cell degranulation through autophagy suppression. SAT1 physically interacts with the long noncoding RNA Cdk19os to inhibit Atg5 and Atg7, disrupting autophagic flux.
Manman Liu, Beiyu Zhang, Junjuan Wang, Yue Jiang, Shiwen Han, Qianwei Wang, Lingyu Zeng, Jinfeng Wang, Huilian Che   +8 more
wiley   +1 more source

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

Advanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng, Zijun Meng, Lan Wei, Pingjing Yang, Fanfan Zhang, Zhiyi Luo, Ting Lai, Chunli Li, Mengyao Zhao, Mengqin Xu, Jiaqi Wang, Linjun Li, Huarong Chen, Jin Li, Ailong Huang, Youquan Bu, Liuyang Zhao   +16 more
wiley   +1 more source

CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells

Advanced Science, EarlyView.
AARS2 functions as an intracellular lactate sensor and lactyltransferase, catalyzing CD112 K412 lactylation to block ubiquitination‐dependent degradation and stabilize CD112. This pathway suppresses CD8+ T‐cell and NK‐cell cytotoxicity, enabling dual immune evasion.
Zhuoshuo Xu, Xinyu Zhang, Fang Dong, Nenghao Shen, Jun Zhou, Zihan Xi, Zhenghao Wu   +6 more
wiley   +1 more source

The inhibitory activity of secretions in cattle against foot and mouth disease virus. [PDF]

Natural and induced factors inhibiting foot and mouth disease virus were investigated in bovine secretions, especially in those from the upper respiratory and oro pharyngeal areas.
Garland, A. J. M
core   +1 more source

Establishment and characterization of mouse lymph node fibrosis models

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu, Xu Guan, Jian Ma, Xin Zhang, Yihang Shi, Jinzhu Zhang, Leiqiong Gao, Wei Chen, Xishan Wang   +8 more
wiley   +1 more source

Important elements of the HACCP process to control Johne\u27s disease, bovine viral diarrhoea virus (BVDV, and bovine leukaemia virus (BLV)

, 2004
The hazard analysis critical control point (HACCP) programme was developed to address food safety issues and has been mandatory in all cattle harvest plants since January 2000.
Pence, Mel, Cole, Dana, Thomson, John U.
core   +1 more source

Persistent infections after natural transmission of bovine viral diarrhoea virus from cattle to goats and among goats [PDF]

, 2013
Bovine viral diarrhoea virus (BVDV) is an economically important pathogen of cattle worldwide. Infection of a pregnant animal may lead to persistent infection of the foetus and birth of a persistently infected (PI) calf that sheds the virus throughout ...
Stalder, H, Stalder, Hanspeter, Peterhans, Ernst, Hilbe, M, Hilbe, Monika, Mathys, Tanja, Zanoni, R, Mathys, T, Vogt, H R, Bachofen, Claudia, Zanoni, Reto Giacomo, Schweizer, M, Bachofen, C, Vogt, Hans-Rudolf, Schweizer, Matthias, Peterhans, E   +15 more
core   +2 more sources

Reproduction of mucosal disease with cytopathogenic bovine viral diarrhoea virus selected in vitro

, 1990
Isolates of non-cytopathogenic bovine viral diarrhoea (BVD) virus from 18 persistently infected calves from one herd were compared by using monoclonal antibodies directed against the major viral glycoprotein gp53.
Moennig, V., Liebler, E., Liess, B., Pohlenz, J., Frey, H. -R.   +4 more
core  

Properties of the bovine viral diarrhoea virus replicase in extracts of infected MDBK cells

, 2000
An assay for the bovine viral diarrhoea virus (BVDV) replicase was developed using extracts from BVDV-infected cells. The replicase activity was maximal approximately 8 h post-infection as measured by the generation of a genomic length radiolabelled RNA.
Greive, S., Gowans, Eric J., Lott, W. B., Gowans, E. J., Warrilow, D.   +4 more
core   +1 more source

Genetic Variability of Pestivirus A (BVDV‐1) Circulating in Cattle From Eastern Turkey

Veterinary Medicine and Science
Background Bovine viral diarrhoea virus (BVDV) infection, caused by Pestiviruses A and B, with various clinical findings and causes significant economic losses.
Fatima Abounaaja, Ali Riza Babaoglu
doaj   +1 more source