Results 61 to 70 of about 4,291 (203)

Risk Factors for Mucosal Involvement in Bullous Pemphigoid and the Possible Mechanism: A Review

Frontiers in Medicine, 2021
Bullous pemphigoid (BP) is the most common type of autoimmune bullous disease and is characterized by the presence of circulating anti-BP180 and/or anti-BP230 autoantibodies.
Xinyi Chen, Wenlin Zhao, Hongzhong Jin, Li Li   +3 more
doaj   +1 more source

Mucous Membrane Pemphigoid After Anti‐PD‐1 Therapy: Risk‐Stratified Management and Treatment Outcomes

International Journal of Dermatology, EarlyView.
ABSTRACT Mucous membrane pemphigoid (MMP) following anti‐programmed cell death‐1 (PD‐1) therapy is rare but increasingly reported. Management of high‐ and low‐risk MMP in this setting and the potential oncologic trade‐offs remain poorly defined. We performed a narrative synthesis of all published cases of anti‐PD‐1‐associated MMP, following MEDLINE ...
Serena Dienes, Negar Esfandiari, Steven Daveluy   +2 more
wiley   +1 more source

Elevated BP180 ELISA at Diagnosis Correlates with Disease Severity and Relapse in Oral Mucous Membrane Pemphigoid: Preliminary Results from a Retrospective Monocentric Italian Study

Applied Sciences
Background: Little is known about the relevance of BP180 ELISA for the clinical management of oral mucous membrane pemphigoid (OMMP). The aim of the present study was to investigate if the levels of anti-BP180 antibodies at diagnosis could be correlated ...
Andrea Gabusi, Davide B. Gissi, Roberto Rossi, Federica Filippi, Camilla Loi, Cosimo Misciali, Giacomo Clarizio, Michelangelo La Placa, Federico Bardazzi   +8 more
doaj   +1 more source

Dipeptidyl Peptidase-4 Inhibitor-Associated Bullous Pemphigoid

Frontiers in Immunology, 2019
Bullous pemphigoid (BP) is an organ-specific autoantibody-mediated blistering skin disease that mainly affects the elderly. Typical clinical features include the widespread blisters, often preceded by and/or associated with itchy urticarial or eczema ...
Kaisa Tasanen, Outi Varpuluoma, Wataru Nishie   +2 more
doaj   +1 more source

Desenvolupament d'un nou model murí humanitzat de pemfigoide ampul·lar obtingut a partir de cèl·lules mare humanes fol·liculars [PDF]

, 2011
El pemfigoid ampul·lar és una malaltia cutània autoimmune. La majoria dels pacients presenten autoanticossos contra proteïnes de la membrana basal de la pell, concretament en contra de la col·làgena XVII, específicament envers el epítop immunodominant, l'
Martínez Escala, MªEstela, Pascual Angulo, Gloria, Universitat Autònoma de Barcelona. Departament de Medicina, Universitat Autònoma de Barcelona. Facultat de Medicina   +3 more
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Bullous Pemphigoid IgG Induces BP180 Internalization via a Macropinocytic Pathway

The American Journal of Pathology, 2013
Bullous pemphigoid (BP) is an autoimmune blistering skin disease induced by pathogenic autoantibodies against a type II transmembrane protein (BP180, collagen type XVII, or BPAG2). In animal models, BP180 autoantibody-antigen interaction appears insufficient to develop blisters, but involvement of complement and neutrophils is required.
Hiroyasu, Sho, Ozawa, Toshiyuki, Kobayashi, Hiromi, Ishii, Masamitsu, Aoyama, Yumi, Kitajima, Yasuo, Hashimoto, Takashi, Jones, Jonathan C.R., Tsuruta, Daisuke   +8 more
openaire   +2 more sources

Molecular genetic studies of a human epidermal autoantigen (the 180-kD bullous pemphigoid antigen/BP180): identification of functionally important sequences within the BP180 molecule and evidence for an interaction between BP180 and alpha 6 integrin. [PDF]

The Journal of cell biology, 1995
The 180-kD bullous pemphigoid autoantigen (BP180) is a component of the hemidesmosome, a cell-matrix connector. This protein is oriented in a type II fashion in the membrane of the hemidesmosome and is a hybrid collagen (classified as type XVII). We have analyzed the fate of various mutant BP180 molecules transfected into several different cell types ...
S B, Hopkinson, S E, Baker, J C, Jones
openaire   +2 more sources

European S2k guidelines on management of autoimmune blistering diseases in children and adolescents

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda, B. Tedbirt, C. Bodemer, M. C. Bolling, M. El Hachem, M. Nikolić, E. Benton, M. Caproni, D. De, D. Didona, K. Drenovska, M. Goebeler, M. Hertl, B. Horváth, M. Kasperkiewicz, D. Kiritsi, M. Larralde, A. V. Marzano, J. Meijer, D. F. Murrell, J. Powell, E. Sprecher, N. S. Chandran, M. M. Tomayko, S. Uzun, N. van Beek, H. Ott, A. Patsatsi, A. Torrelo, A. Welfringer‐Morin, E. Schmidt, P. Joly   +31 more
wiley   +1 more source

Association of Autoantibodies to BP180 with Disease Activity in Greek Patients with Bullous Pemphigoid

Clinical and Developmental Immunology, 2012
39 bullous pemphigoid (BP) patients were studied to assess the clinical significance of anti-BP180 and anti-BP230 circulating autoantibodies of BP and correlate their titers with the clinical scores of the BP Disease Area Index (BPDAI) and the Autoimmune
Aikaterini Patsatsi, Aikaterini Kyriakou, Aikaterini Pavlitou-Tsiontsi, Anastasia Giannakou, Dimitrios Sotiriadis   +4 more
doaj   +1 more source

Pemfigoidin komorbiditeetit, kliininen kuva ja lääkehoito : retrospektiivinen tutkimus HYKS:issä [PDF]

, 2016
Tutkimuksen tavoitteena oli kartoittaa pemfigoidiin liittyviä edeltäviä sairauksia ja lääkityksiä suomalaisessa potilasotoksessa. Pohjoiseurooppalaisia tutkimuksia aiheesta ei ole tehty.
Pankakoski, Anna
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