Results 81 to 90 of about 567,455 (203)

The kallikrein-Kinin system modulates the progression of colorectal liver metastases in a mouse model

BMC Cancer, 2018
Background The Kallikrein-Kinin System (KKS) has been found to play a role in tumor progression in several cancers. The KKS metabolic cascade depends on signalling through two cross talking receptors; bradykinin receptor 1 (B1R) and bradykinin receptor 2
Patricia Luiza Nunes da Costa, David Wynne, Theodora Fifis, Linh Nguyen, Marcos Perini, Christopher Christophi   +5 more
doaj   +1 more source

A novel anti-thrombotic mechanism mediated by the receptors of the kallikrein/kinin and renin-angiotensin systems

Frontiers in Medicine, 2016
The contact activation (CAS) and kallikrein/kinin (KKS) systems regulate thrombosis risk two ways. First, the CAS influences contact activation-induced factor XI activation and thrombin formation through the hemostatic cascade.
Alvin H. Schmaier
doaj   +1 more source

Stimulation of Na⁺/H⁺ Exchanger Isoform 1 Promotes Microglial Migration [PDF]

, 2013
Regulation of microglial migration is not well understood. In this study, we proposed that Na+/H+ exchanger isoform 1 (NHE-1) is important in microglial migration.
Cengiz, P, Yuan Hui, Baba, Akemichi, Vishal Chanana, Chanana, V, Dong Kim (443919), Shi Yejie, Sun Dandan, Dandan Sun, Zhang, Zhe, Hui Yuan, Sun, Dandan, Toshio Matsuda, Yejie Shi, Akemichi Baba, An Sun, Matsuda Toshio, Peter Ferrazzano, Matsuda, Toshio, Pelin Cengiz, Akemichi Baba (253010), Baba, A, Shi, Y, Ferrazzano, Peter, Ferrazzano Peter, Hui Yuan (402180), Kim, Dong, Dong Kim, Sun, D, Vishal Chanana (448559), Shi, Yejie, Cengiz, Pelin, Toshio Matsuda (448560), Ferrazzano, P, Matsuda, T, Yuan, H, Peter Ferrazzano (448562), Dandan Sun (448563), Kim, D, Chanana, Vishal, Baba Akemichi, Pelin Cengiz (448561), Cengiz Pelin, Yuan, Hui, Yejie Shi (448558), Kim Dong, Chanana Vishal   +46 more
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THE CORONARY VASCULATURE AND THE MYOCARDIUM

Journal of Biological Research, 1999
It has been reported that the activity of bradykinin on vascular endothelial receptors results in vasodilatation ( 1-3) due to the release of both nitric oxide (NO) and the so called endothelial-derived hyperpolarizing factor (EDHF) (4-7).
F. Ceresa, A. Delfino, A. De Matteis, N. Ferrero, M. Novarino, A. Rittà   +5 more
doaj  

An uncommon case of postpartum venous thrombosis in a patient with hereditary angioedema. Patient from the ITACA Cohort (Italian Network for Hereditary and Acquired Angioedema)

Italian Journal of Medicine
Hereditary angioedema (HAE) is a rare genetic condition characterized by episodes of cutaneous or submucosal edema, most commonly affecting the skin, the abdomen, and the upper respiratory tract. The most common cause of HAE is either a deficiency (type
Francesco Giardino, Andrea Caruso, Simone Giosuè Longhitano, Lorena Domenica Campanello   +3 more
doaj   +1 more source

Kinin B1- and B2-Receptor Subtypes Contract Isolated Bovine Ciliary Muscle: Their Role in Ocular Lens Function and Intraocular Pressure Reduction

Pharmaceuticals
Background: Bradykinin is an endogenously produced nonapeptide with many physiological and pathological functions that are mediated by two pharmacologically defined receptor subtypes, B1- and B2-receptors.
Najam A. Sharif, Madura Kulkarni-Chitnis, Anthonia Okolie, Ya Fatou Njie-Mbye, Sunny E. Ohia   +4 more
doaj   +1 more source

Papel dos receptores cininérgicos na neuropatia periférica induzida pelo quimioterápico paclitaxel [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduaçao em Farmacologia, Florianópolis, 2013A neuropatia periférica induzida por quimioterápicos (NPIQ) é uma das principais causas de dor ...
Costa, Robson da
core  

Papel do receptor ativado por proteinases-2 (par-2) no comportamento de coçar em camundongos [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pos-Graduação em Farmacologia, Florianópolis, 2009.O objetivo do presente estudo foi investigar os possíveis mecanismos e mediadores envolvidos no
Costa, Robson da
core  

Icatibant, an inhibitor of bradykinin receptor 2, for hereditary angioedema attacks: prospective experimental single-cohort study

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Hereditary angioedema (HAE) with C1 inhibitor deficiency manifests as recurrent episodes of edema involving the skin, upper respiratory tract and gastrointestinal tract. It can be lethal due to asphyxia.
Regis Albuquerque Campos, Solange Oliveira Rodrigues Valle, Alfeu Tavares França, Elisabete Cordeiro, Faradiba Sarquis Serpa, Yara Ferreira Mello, Teresinha Malheiros, Eliana Toledo, Elie Mansour, Gustavo Fusaro, Anete Sevciovic Grumach   +10 more
doaj   +1 more source

Envolvimento dos receptores B1 e B2 das cininas no extravasamento plasmático induzido pela bradicinina e desArg9-bradicinina na dura-máter de ratos [PDF]

, 2004
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.Envolvimento dos receptores B1 e B2 das cininas no extravasamento plasmático (EP) induzido pela bradicinina (BK) e ...
Waltrick, Pablo Tortato
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