Results 1 to 10 of about 5,853 (186)
Bradykinin B2 receptor blockade and intradialytic hypotension
BMC Nephrology, 2023 Introduction Intradialytic hypotension (IDH) is a common clinical complication and is associated with increased morbidity and mortality in patients undergoing maintenance hemodialysis (MHD).
Jorge L. Gamboa +6 more
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The bradykinin B2 receptor as a context-dependent modulator of neural circuit function [PDF]
Frontiers in Cellular NeuroscienceThe kallikrein–kinin system (KKS) is a proteolytic signaling pathway traditionally associated with vascular regulation and inflammation, but increasing evidence indicates that its components are also expressed in the central nervous system.
Juliene L. S. Silva +3 more
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Kinin-B2 receptor mediated neuroprotection after NMDA excitotoxicity is reversed in the presence of kinin-B1 receptor agonists. [PDF]
PLoS ONE, 2012 Kinins, with bradykinin and des-Arg(9)-bradykinin being the most important ones, are pro-inflammatory peptides released after tissue injury including stroke.
Antonio H Martins +7 more
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Frontiers in Endocrinology, 2022 The angiotensin type 2 (AT2) receptor and the bradykinin type 2 (B2) receptor are G protein-coupled receptors (GPCRs) that have major roles in the cardiovascular system. The two receptors are known to functionally interact at various levels, and there is
Elizabeth K. M. Johnstone +15 more
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The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. [PDF]
PLoS ONE, 2013 BACKGROUND: Cell senescence is central to a large body of age related pathology, and accordingly, cardiomyocytes senescence is involved in many age related cardiovascular diseases.
Ruolan Dong +7 more
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Can’t Intubate, Can’t Oxygenate: A Rare Case of a Difficult Airway due to Nonhereditary Angioedema
Acta Clinica Croatica, 2022 Angioedema is a form of allergic mediated by histamine and non-allergic mediated by bradykinin and can be lethal if not recognized and treated promptly.
Điđi Delalić +2 more
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Receptor mechanism of infarct-limiting effect of adaptation to normobaric hypoxia
Бюллетень сибирской медицины, 2021 The aim of the study was to investigate the involvement of bradykinin, cannabinoid and vanilloid (TRPV1 channel) receptors in the implementation of the infarct-limiting effect of chronic normobaric hypoxia (CNH).Materials and methods.
N. V. Naryzhnaya +3 more
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Egyptian Journal of Medical Human Genetics, 2018 Background: Angiotensin-converting enzyme (ACE) inhibitors-related cough had been reported to contribute for discontinuation of ACE inhibitors therapy.
Mohammad Saifur Rohman +7 more
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In Vitro Pharmacological Profile of a New Small Molecule Bradykinin B2 Receptor Antagonist
Frontiers in Pharmacology, 2020 We here report the discovery and early characterization of Compound 3, a representative of a novel class of small molecule bradykinin (BK) B2 receptor antagonists, and its superior profile to the prior art B2 receptor antagonists Compound 1 and Compound ...
Anne Lesage +8 more
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