Results 21 to 30 of about 6,163 (183)

Thromboxane A2 mediates cation-induced airway hyperresponsiveness through the bradykinin B2 receptor in guinea pigs

Allergology International, 1999
To elucidate the mechanisms of cationic protein-induced airway hyperresponsiveness (AHR), the airway response to methacholine, and the concentrations of thromboxane B2 (TXB2) and 6-keto-PGF1α in the bronchoalveolar lavage fluid (BALF) of guinea-pigs were
Tomohiko Shirotani, Hitoshi Maeda, Yoshihiro Nishimura, Mitsuhiro Yokoyama   +3 more
doaj   +1 more source

Algorithms in Allergy: Hereditary Angioedema. [PDF]

Allergy
Allergy, Volume 81, Issue 8, Page 3008-3012, August 2026.
Bork K, Magerl M, Aygören-Pürsün E, Farkas H.   +3 more
europepmc   +2 more sources

Bradykinin receptors in intestinal smooth muscles and their post-receptor events related to calcium

Mediators of Inflammation, 1993
The effects of trifluoperazine and verapamil on bradykinin- and des-Arg9-bradykinin induced responses of isolated rat duodenum and guinea-pig ileum were investigated to elucidate post-bradykinin receptor events.
Yusuf Öztürk, V. Melih Altan, Nuray Yıdızoğlu-Arı, Orhan Altınkurt   +3 more
doaj   +1 more source

Neuroprotection of bradykinin/bradykinin B2 receptor system in cerebral ischemia

Biomedicine & Pharmacotherapy, 2017
Bradykinin B2 receptor (B2R) activated by its endogenous ligand bradykinin participates in various physiological processes including neurogenesis, neuronal differentiation, and control of inflammation and blood pressure. Besides these effects, B2R has been demonstrated to protect neurons from ischemia/reperfusion (I/R) injury.
Bingyuan, Ji, Baohua, Cheng, Yanyou, Pan, Chunmei, Wang, Jing, Chen, Bo, Bai   +5 more
openaire   +2 more sources

Neprilysin Inhibitors Potentiate Effects of Bradykinin on B2 Receptor [PDF]

Hypertension, 2002
Some beneficial effects of angiotensin-I–converting enzyme (ACE, kininase II) inhibitor therapy are attributed to enhancing the activity of bradykinin on its B 2 receptor. Independent of inhibition of bradykinin hydrolysis, ACE inhibitors enhance the action of bradykinin on its B 2 receptor ...
Peter A, Deddish, Branislav M, Marcic, Fulong, Tan, Herbert L, Jackman, Zhenlong, Chen, Ervin G, Erdös   +5 more
openaire   +2 more sources

Increased Reactive Oxygen Species Generation Contributes to the Atherogenic Activity of the B2 Bradykinin Receptor

Frontiers in Medicine, 2019
Atherosclerosis and ensuing cardiovascular disease are major causes of death with insufficient treatment options. In search for pathomechanisms of atherosclerosis, we investigated the impact of the B2 bradykinin receptor, Bdkrb2, on atherosclerotic ...
Alexander Perhal, Stefan Wolf, Yahya F. Jamous, Andreas Langer, Joshua Abd Alla, Ursula Quitterer, Ursula Quitterer   +6 more
doaj   +1 more source

Neuroprotective Effects of Kinin B2 Receptor in Organotypic Hippocampal Cultures of Middle-Aged Mice

Frontiers in Aging Neuroscience, 2019
Aging is a multifactorial phenomenon that results in several changes at cellular and molecular levels and is considered the main risk factor for some neurodegenerative diseases. Several evidence show the participation of the kallikrein-kinin system (KKS)
Mariana Toricelli, Mariana Toricelli, Sebastiana Ribeiro Evangelista, Sebastiana Ribeiro Evangelista, Larissa Rolim Oliveira, Tania Araujo Viel, Tania Araujo Viel, Hudson Sousa Buck, Hudson Sousa Buck   +8 more
doaj   +1 more source

P4.11 LOWER LIMB VASOMOTOR AND FIBRINOLYTIC EFFECTS OF KININ RECEPTOR AGONISTS IN MAN

Artery Research, 2009
Background: Vascular B1 kinin receptor expression is upregulated in human atheroma and the presence of angiotensin-converting enzyme inhibition (ACEi), but its role in man remains unclear.
N.L. Cruden, N.N. Lang, T.J. MacGillivray, N.G. Uren, K.A. Fox, D.E. Newby   +5 more
doaj   +1 more source

Endoplasmic Reticulum Is a Key Organella in Bradykinin-Triggered ATP Release From Cultured Smooth Muscle Cells

Journal of Pharmacological Sciences, 2007
ATP has broad functions as an autocrine/paracrine molecule. The mode of ATP release and its intracellular source, however, are little understood. Here we show that bradykinin via B2-receptor stimulation induces the extracellular release of ATP via the ...
Yumei Zhao, Keisuke Migita, Chiemi Sato, Sadaharu Usune, Takahiro Iwamoto, Takeshi Katsuragi   +5 more
doaj   +1 more source

The Bradykinin B2 Receptor Agonist (NG291) Causes Rapid Onset of Transient Blood–Brain Barrier Disruption Without Evidence of Early Brain Injury

Frontiers in Neuroscience, 2021
Background: The blood–brain barrier (BBB) describes the brain’s highly specialized capillaries, which form a dynamic interface that maintains central nervous system (CNS) homeostasis.
Sergio R. Rodríguez-Massó, Michelle A. Erickson, Michelle A. Erickson, William A. Banks, William A. Banks, Henning Ulrich, Antonio Henrique Martins   +6 more
doaj   +1 more source