Results 11 to 20 of about 6,163 (183)

Registry-Based Analysis of Treatment and Retreatment Attacks of Hereditary Angioedema. [PDF]

Clin Exp Allergy
Clinical &Experimental Allergy, Volume 56, Issue 8, Page 986-988, August 2026.
Hakl R, Baroš J, Sobotková M, Zachová R, Králíčková P, Vachová M, Krčmová I, Svoboda M, Szmucová V, Skotáková M, Litzman J.   +10 more
europepmc   +2 more sources

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Intraprocedural Hemodynamics During Concomitant Rheocarna Therapy and Maintenance Hemodialysis: Effects of Dialyzer Membrane Type and Circuit Sequence. [PDF]

J Clin Apher
ABSTRACT Chronic limb‐threatening ischemia (CLTI), a severe manifestation of peripheral artery disease, is particularly prevalent among patients receiving maintenance hemodialysis (HD) and is associated with poor limb and survival outcomes. Low‐density lipoprotein (LDL) apheresis, including Rheocarna, is used as adjunctive therapy for refractory CLTI ...
Ishizuka Y, Sato G, Ishigaki S, Enoki R, Kajiwara K, Nakasato A, Kinomura S, Kin S, Noguchi Y, Yoshizawa D, Kikuchi K, Abe M, Kumagai K, Tanaka T, Okamoto K.   +14 more
europepmc   +2 more sources

The Pathophysiology of Hereditary Angioedema

World Allergy Organization Journal, 2010
Hereditary angioedema (HAE) causes recurrent episodes of angioedema that may be very severe and are frequently associated with significant morbidity and even mortality. Understanding the pathophysiology of this disease is crucial for proper diagnosis and
Bruce L Zuraw, MD
doaj   +1 more source

Polymorphisms in the Bradykinin B2 Receptor Gene and Childhood Asthma [PDF]

Biological Chemistry, 2001
Bradykinin has been suggested as one of the key mediators of bronchial asthma. Polymorphisms with a potential functional relevance have been described in the B2 bradykinin receptor gene. Study of these polymorphisms in 77 children with asthma and 73 controls revealed no association. However, when comparing the asthmatics according to their age at onset
Kusser, B., Braun, A., Praun, M., Illi, S., Mutius, Erika von, Roscher, A. A.   +5 more
openaire   +3 more sources

Ranakinestatin-PPF from the Skin Secretion of the Fukien Gold-Striped Pond Frog, Pelophylax plancyi fukienensis: A Prototype of a Novel Class of Bradykinin B2 Receptor Antagonist Peptide from Ranid Frogs

The Scientific World Journal, 2014
The defensive skin secretions of many amphibians are a rich source of bradykinins and bradykinin-related peptides (BRPs). Members of this peptide group are also common components of reptile and arthropod venoms due to their multiple biological functions
Jie Ma, Yu Luo, Lilin Ge, Lei Wang, Mei Zhou, Yingqi Zhang, Jinao Duan, Tianbao Chen, Chris Shaw   +8 more
doaj   +1 more source

Different Prostanoids Are Involved in Bradykinin-Induced Endothelium-Dependent and -Independent Vasoconstriction in Rat Mesenteric Resistance Arteries

Journal of Pharmacological Sciences, 2004
Mechanisms underlying bradykinin-induced vasoconstriction were investigated in rat perfused mesenteric vascular beds with active tone. In preparations with intact endothelium, bolus injections of bradykinin (1 to 1,000 pmol) dose-dependently produced ...
Hideki Nawa, Yuji Kurosaki, Hiromu Kawasaki   +2 more
doaj   +1 more source

Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice

Nature Communications, 2023
An important role for liver in the regulation of adipose tissue thermogenesis upon cold exposure has been suggested; however, the underlying mechanisms remain incompletely defined.
Fei Xiao, Haizhou Jiang, Zi Li, Xiaoxue Jiang, Shanghai Chen, Yuguo Niu, Hanrui Yin, Yousheng Shu, Bo Peng, Wei Lu, Xiaoying Li, Zhigang Li, Shujue Lan, Xiaoyan Xu, Feifan Guo   +14 more
doaj   +1 more source

Signaling Pathways Mediating Bradykinin-Induced Contraction in Murine and Human Detrusor Muscle

Frontiers in Medicine, 2022
Bradykinin (BK) has been proposed to modulate urinary bladder functions and implicated in the pathophysiology of detrusor overactivity. The present study aims to elucidate the signaling pathways of BK-induced detrusor muscle contraction, with the goal of
Kinga Borsodi, Helga Balla, Péter József Molnár, Péter József Molnár, Ádám Lénárt, István Kenessey, András Horváth, Attila Keszthelyi, Miklós Romics, Attila Majoros, Péter Nyirády, Stefan Offermanns, Zoltán Benyó   +12 more
doaj   +1 more source

Regulation of bradykinin B₂‐receptor expression by oestrogen [PDF]

British Journal of Pharmacology, 1997
Tissue kallikrein is overexpressed in the kidney of female rats, this sexual dimorphism being associated with a greater effect of early blockade of bradykinin B2‐receptors on female blood pressure phenotype. We evaluated the effect of ovariectomy and oestradiol benzoate (50 μg kg−1 every two days for two weeks) on the vasodepressor response to intra ...
Madeddu P, Emanueli C, Song Q, VARONI, Maria Vittoria, DEMONTIS, Maria Piera, Anania V, GLORIOSO, Nicola Filippo, Chao J. Br J. P.h.a.r.m.a.c.o.l. 1997 Aug, 121:1763 9. Erratum in: Br J. Pharmacol 1998 Apr, 123:742   +9 more
openaire   +5 more sources