Results 161 to 170 of about 174,356 (352)

Supplementary Figures 1-2 from In Melanoma, <i>RAS</i> Mutations Are Accompanied by Switching Signaling from BRAF to CRAF and Disrupted Cyclic AMP Signaling

, 2023
Nicolas Dumaz, Robert Hayward, Jan M. L. Martin, Lesley A. Ogilvie, Douglas Hedley, John A. Curtin, Boris C. Bastian, Caroline J. Springer, Richard Marais   +8 more
openalex   +2 more sources

530 Analysis of BRAF mutation and expression of NGFR and P16 in nevus and melanoma [PDF]

, 2021
Jianglong Feng, Wen Zeng, Hongyun Lu
openalex   +1 more source

BRAF [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Small Nucleotide Variant Analysis Using RNA Fusion Panel (SMURF): Making the Most of RNAseq Data in Solid Tumours

Journal of Clinical Laboratory Analysis, EarlyView.
RNA‐based fusion panels using targeted next‐generation sequencing of formalin‐fixed paraffin‐embedded (FFPE) tumour tissue specimens have been used for a few years from patients with various tumour types to detect rearrangements/fusions. Using the bioinformatic approaches the data obtained from RNA sequencing (RNAseq) can also be used for small ...
Pranav Dorwal, Julie Robin, Broden Krause, Patricia Pyrchla, Bin Yuan, Robert Quach, Anna Fong Na Goh, Pamela Htain, Noel Djitro, Amit Kumar, Liyan Song, Priscillia Siswara, Suzanne Svobodova, Peter Kaub, Beena Kumar   +14 more
wiley   +1 more source

Artificial intelligence strategies for predicting kinase inhibitor resistance: A comprehensive review of methods, challenges, and future perspectives

Journal of Intelligent Medicine, EarlyView.
Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan, Mohanad Ali Deifallah, Alaa Zaghloul, Rania Elgohary   +3 more
wiley   +1 more source

Preoperative BRAF(V600E) mutation screening is unlikely to alter initial surgical treatment of patients with indeterminate thyroid nodules [PDF]

, 2012
David A. Kleiman, Matthew J. Sporn, Toni Beninato, Michael J. Crowley, Anvy Nguyen, Alessia Uccelli, Theresa Scognamiglio, Rasa Zarnegar, Thomas J. Fahey   +8 more
openalex   +1 more source

BRAF Mutations and Resistance of Non-Small Cell Lung Cancer to BRAF-Targeted Therapies Using Liquid Biopsy

, 2021
Ming Li, Xiaoying Zhang
openalex   +1 more source

Identification of Predictive Factors for Isolated Brain Progression in Patients With Cerebral Metastatic Melanoma After Treatment With Stereotactic Brain Radiotherapy

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Melanomas often metastasize to the brain, leading to a significantly poor prognosis despite advances in local and systemic treatments. In clinical practice, we frequently observe varying response patterns and progression dynamics between cerebral and extra cerebral sites. Objectives This study aims to identify predictive factors for
Manuel Croix, Justine Lequesne, Julien Geffrelot, Anne Dompmartin, Jean Matthieu L'orphelin   +4 more
wiley   +1 more source

Metabolic Parameters on Baseline and Early [18F]FDG PET/CT as a Predictive Biomarker for Resistance to BRAF/MEK Inhibition in Advanced Cutaneous BRAFV600-mutated Melanoma [PDF]

Bernies van der Hiel, Berlinda J. de Wit–van der Veen, Alfons J.M. van den Eertwegh, Wouter V. Vogel, Marcel P. M. Stokkel, Marta López‐Yurda, Ronald Boellaard, Ellen Kapiteijn, Geke A.P. Hospers, Maureen J.B. Aarts, Filip De Vos, Marye J. Boers‐Sonderen, Astrid A.M. van der Veldt, Jan Willem B. de Groot, John B.A.G. Haanen   +14 more
openalex   +1 more source

Indirect Comparison of Combined BRAF and MEK Inhibition in Melanoma Patients with Elevated Baseline Lactate Dehydrogenase

, 2020
Valerie Glutsch, Teresa Amaral, Claus Garbe, K.-M. Thoms, Peter Mohr, Axel Hauschild, Bastian Schilling   +6 more
openalex   +2 more sources