Results 191 to 200 of about 174,356 (352)

Trattamento con FOLFIRI e aflibercept in paziente con adenocarcinoma del colon destro RAS e BRAF wild-type e metastasi epatiche potenzialmente resecabili [PDF]

, 2018
Filippo Pietrantonio
openalex   +1 more source

Evolving Features of RASopathies Among Pregnancies With Abnormal Fetal Fluid Collections

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective We aimed to characterize the fetal features across gestation and describe genotype‐phenotype correlations for pregnancies with fetal RASopathies that were more severely affected as they presented with at least one abnormal fluid collection.
Natalie B. Gulrajani, John Boscardin, Billie R. Lianoglou, Katie Tick, Carmen M. A. Santoli, Kristen A. Miller, Angie C. Jelin, Lorraine Dugoff, Rose Giardine, Cori Feist, Rachel Pilliod, Stephanie Dukhovny, Kelly Gilmore, Neeta L. Vora, Aisling Murphy, Peter N. Robinson, Mary E. Norton, Teresa N. Sparks   +17 more
wiley   +1 more source

Concomitant <i>RAS</i> and <i>BRAF</i> V600E Mutations in Unresectable Metastatic CRC: A Case of Long-term Survival. [PDF]

J Anus Rectum Colon
Kitagawa K, Takahashi N, Fukuda M, Hannya Y, Kurita S, Shimoyama Y, Kumamoto T, Toya N, Eto K.   +8 more
europepmc   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

The BRAF V600E/MEK/ERK/METTL3 positive feedback loop regulates autophagy and promotes stemness and invasiveness in glioblastoma via m⁶A modification. [PDF]

J Exp Clin Cancer Res
Xie Y, Li Y, Tang M, Li Z, Hu W, Qiu X, Wang C, Zou Y, Lu J, Yuan Z, Chen F, Yang Y, Lu C, Sai K, Guo Y, He Z, Duan H, Mou Y.   +17 more
europepmc   +1 more source

Challenges in the treatment of BRAF K601E-mutated lung carcinoma: a case report of rapid response and resistance to dabrafenib and trametinib [PDF]

Akihiro Nishiyama, Shigeki Sato, Hiroyuki Sakaguchi, Hiroshi Kotani, Kaname Yamashita, Koushiro Ohtsubo, Shigeki Nanjo, Seiji Yano, Keishi Mizuguchi, Hiroko Ikeda, Shinji Takeuchi   +10 more
openalex   +1 more source

Prognostic Significance of the Modified Glasgow Prognostic Score in Patients With Stage IV Melanoma Receiving Immune Checkpoint Inhibitors: A Single‐Center Retrospective Study

The Journal of Dermatology, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for malignant melanoma (MM). However, given variable response rates and potential toxicities, identifying robust biomarkers is crucial. We investigated whether the modified Glasgow Prognostic Score (mGPS) predicts treatment efficacy and toxicity in Asian patients with
Ken Horisaki, Shusuke Yoshikawa, Wataru Omata, Arata Tsutsumida, Yoshio Kiyohara   +4 more
wiley   +1 more source

Association of oncogene mutations with clinical and histopathological characteristics in patients with metastatic melanoma. [PDF]

An Bras Dermatol
Quintiliano JA, Nunes AF, Pinheiro-Hubinger-Stauffer L.   +2 more
europepmc   +1 more source

BRAF; KIAA1549 [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Dissecting the MAPK signaling landscape in malignant melanoma: from BRAF and NRAS mutations to precision combination therapies. [PDF]

Front Cell Dev Biol
Fang X, Wang S, Fu S.
europepmc   +1 more source