Results 251 to 260 of about 119,295 (311)

V600E biases the BRAF kinase domain toward an activation-compatible conformational ensemble through long-range dynamic rewiring. [PDF]

RSC Adv
Zhang BD, Xi Q, Ying YM, Zhao DR, Yang LQ, Sang P.   +5 more
europepmc   +1 more source

Artificial Intelligence-Based Prediction of Molecular Alterations in Colorectal Cancer Using Routine H&E Whole-Slide Images. [PDF]

Int J Mol Sci
Popa MF, Șiancu P, Mohor CI, Oprinca-Muja LA, Oprinca GC, Mohor CI, Tănăsescu C, Tănăsescu D, Cristian A, Vereș VV, Bereanu A.   +10 more
europepmc   +1 more source

Investigation of Oncogenic Gene Mutation and Associated Protein Expression in Ameloblastic Carcinoma

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to investigate gene mutations in ameloblastic carcinoma (AC) including BRAF, KRAS, and PIK3CA, along with associated protein expressions of BRAF V600E, p‐ERK1/2, and p‐mTOR, which represent activation of MAPK/ERK and PI3K/mTOR pathways, respectively.
Puangwan Lapthanasupkul, Jintana Pankam, Siribang‐on Piboonniyom Khovidhunkit, Prapapun Seneetuntigul, Nakarin Kitkumthorn   +4 more
wiley   +1 more source

Circulating tumour DNA to guide rechallenge with cetuximab plus irinotecan in RAS/BRAF wild-type metastatic colorectal cancer: A nonrandomised clinical trial. [PDF]

Clin Transl Med
Wang DS, Chen WC, Ren C, Wang FH, Wang ZQ, Luo HY, Wang F, Tan Q, Li YH.   +8 more
europepmc   +1 more source

Epigenetic signatures of attention problems in youth with childhood exposure to family and community violence

Psychiatry and Clinical Neurosciences, EarlyView.
Aim The link between violence‐related epigenetic changes and attentional problems (APs) is still not well understood. This article examines if exposure to family and community violence during childhood and adolescence may shape DNA methylation patterns associated with attention in youth.
Renata Queiroz Ramos, Adriane Feijó Evangelista, Cosme Marcelo Furtado Passos da Silva, Fernanda Serpeloni, Joviana Quintes Avanci, Natasha Reis Lacerda, Simone Gonçalves de Assis   +6 more
wiley   +1 more source

HuR degradation reveals dependencies in BRAF-driven cancers. [PDF]

Trends Cancer
Siordia IR, Brody JR, Dixon DA.
europepmc   +1 more source

Molecular therapy for papillary craniopharyngioma: a multi-institutional analysis of practice patterns across the RAPID Consortium. [PDF]

J Neurooncol
Damante MA, Juncker RB, Little AS, Van Gompel JJ, Palit S, Pacione DR, Barkhoudarian G, Sivakumar W, Blackburn S, Mendoza MM, Evans JJ, Benjamin C, Palmer JD, Giglio P, Prevedello DM, Wu KC, RAPID Consortium.   +16 more
europepmc   +1 more source

Distinct molecular profiles of indeterminate and malignant thyroid nodules in patients under 21 years of age. [PDF]

Endocr Relat Cancer
Ricarte-Filho JC, Castellanos L, Waguespack SG, Bryan J, Alshalalfa M, Cavazos TB, Chen Y, Bauer A, Klopper JP, Kloos RT, Franco AT.   +10 more
europepmc   +1 more source

The past, present, and future treatment of BRAF^V600-mutant metastatic colorectal cancer: A comprehensive review. [PDF]

Cancer
Dirven I, Ang C, Bertels C, Kortbeek K, de Haar-Holleman A, Vollebergh M, Poulikakos P, Neyns B.   +7 more
europepmc   +1 more source