Results 271 to 280 of about 174,356 (352)

Endoscopic features of deficient mismatch repair/microsatellite instability‐high and BRAF‐mutated colorectal cancer

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Objective Recent advancements in genome analyses, including the BRAF gene and mismatch repair (MMR) gene/microsatellite instability (MSI), have revealed the biological diversity of colorectal cancer (CRC). BRAF‐mutated CRC has a poor prognosis; however, cases exhibiting deficient MMR (dMMR)/MSI‐high (MSI‐H) and BRAF gene mutations have ...
Rika Omote, Shizuma Omote, Ryohei Sumii, Joichiro Horii, Isao Fujita, Hideaki Miyaso, Tatsuya Toyokawa, Masaru Inagaki   +7 more
wiley   +1 more source

Dedifferentiation and Redifferentiation of Follicular-Cell-Derived Thyroid Carcinoma: Mechanisms and Therapeutic Implications. [PDF]

Biomedicines
He Y, Tang Z, Xu M, Huang T.
europepmc   +1 more source

A Case of Human Epidermal Growth Factor Receptor 2‐Positive Colon Cancer With Invasive Micropapillary Carcinoma Component

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT A female patient in her 60s tested positive for the fecal occult blood test while undergoing health screening. Colonoscopy revealed a 15‐mm‐sized flat elevated lesion with a central depression in the sigmoid colon. Narrow‐band imaging magnification revealed a Japan Narrow‐Band Imaging Expert Team classification of type 2B, whereas crystal ...
Masashi Kono, Yoriaki Komeda, Hiroshi Kashida, Satoru Hagiwara, Akihiro Yoshida, Shunsuke Omoto, Mamoru Takenaka, Naoko Tsuji, George Tribonias, Masatoshi Kudo   +9 more
wiley   +1 more source

Gastric Foveolar‐Type Hyperplastic Polyp of the Duodenum With GNAS and KRAS Mutations: A Potential Precursor to Neoplasia

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT We report a gastric foveolar‐type hyperplastic polyp of the duodenum harboring mutations in the GNAS and KRAS genes. The lesion was incidentally detected during a routine upper gastrointestinal endoscopy in a man in his 50s. It appeared as a 10‐mm elevated lesion located at the superior duodenal angle.
Kenji Yamazaki, Ryoji Kushima, Noritaka Ozawa, Haruka Koizumi, Saeka Hayashi, Atsushi Soga, Koji Yamashita, Shogo Shimizu, Masahito Shimizu   +8 more
wiley   +1 more source

Figure S3 from Ccr2⁺ monocyte-derived macrophages influence trajectories of acquired therapy resistance in <i>Braf</i>-mutant melanoma

Dahihm Kim, Luye An, Jiwon Moon, Viviana I. Maymí, Alexander I. McGurk, Brian D. Rudd, Deborah J. Fowell, Andrew C. White   +7 more
openalex   +1 more source

Impact of melanoma histological regression on first‐line immunotherapy response in stage‐IV disease

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Jean‐Baptiste Such, Sandrine Mansard, Mélissa Zlobecki, Carole Chevenet, Céline Lambert, Marie Bachelerie, Jacques Rouanet   +6 more
wiley   +1 more source

Clinicopathological Characteristics With the Status of Mismatch Repair Deficient Invasive Colorectal Cancer With Spontaneous Regression

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Spontaneous regression of endoscopically invasive colorectal cancer (CRC) after biopsy has been rarely reported. We report three cases of endoscopically invasive CRC with spontaneous regression after biopsy and a review of the literature regarding spontaneous regression of CRC with somatic mismatch repair deficiency (MMR‐d).
Fumiya Okano, Naohisa Yoshida, Yukiko Morinaga, Naoto Iwai, Reo Kobayashi, Ken Inoue, Osamu Dohi, Takashi Ando, Yoshito Itoh   +8 more
wiley   +1 more source

Detection of KRAS, NRAS and BRAF Mutations in Liquid Biopsy from Patients with Colorectal Cancer. [PDF]

Oncol Res
Ondraskova K, Cwik M, Horky O, Berkovcova J, Holcakova J, Bartosik M, Kazda T, Mrazova K, Uher M, Kiss I, Hrstka R.   +10 more
europepmc   +1 more source

Supplementary Table S1 from A Phase II Redifferentiation Trial with Dabrafenib-Trametinib and 131I in Metastatic Radioactive Iodine Refractory BRAF p.V600E Mutated Differentiated thyroid Cancer

Sophie Leboulleux, Christine Do Cao, Slimane Zerdoud, Marie Attard, Claire Bournaud, Ludovic Lacroix, Danielle Benisvy, David Taïeb, Stéphane Bardet, Marie Terroir-Cassou-Mounat, Nadège Anizan, Emilie Bouvier-Morel, Livia Lamartina, Georges Lion, Sarah Bétrian, Christophe Sajous, Aurélie Schiazza, Marie-Eve Garcia, Renaud Ciappuccini, Martin Schlumberger, Abir Al Ghuzlan, Yann Godbert, Isabelle Borget   +22 more
openalex   +1 more source

Conversion Surgery after Chemotherapy in a Stage IV BRAF V600E‐Mutated Laterally Spreading Tumor With Neuroendocrine Component

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT We report a rare case of a BRAF V600E‐mutated laterally spreading tumor, granular type (LST‐G), with a neuroendocrine carcinoma (NEC) component in a patient with stage IV colorectal cancer. The patient presented with multiple lymph nodes and liver metastases.
Reona Kawamura, Naoya Toyoshima, Masau Sekiguchi, Hiroyuki Takamaru, Masayoshi Yamada, Nozomu Kobayashi, Hidekazu Hirano, Yasuyuki Takamizawa, Taiki Hashimoto, Yutaka Saito   +9 more
wiley   +1 more source