Results 101 to 110 of about 102,854 (205)

Selection of patients with germline MLH1 mutated Lynch syndrome by determination of MLH1 methylation and BRAF mutation [PDF]

, 2018
Lynch syndrome is one of the most common hereditary colorectal cancer (CRC) syndrome and is caused by germline mutations of MLH1, MSH2 and more rarely MSH6, PMS2, MLH3 genes.
Benhattar, Jean, Bouzourene, Hanifa, Hutter, Pierre, Losi, Lorena, Martin, Patricia   +4 more
core  

Mapping genetic interactions in cancer: a road to rational combination therapies. [PDF]

, 2019
The discovery of synthetic lethal interactions between poly (ADP-ribose) polymerase (PARP) inhibitors and BRCA genes, which are involved in homologous recombination, led to the approval of PARP inhibition as a monotherapy for patients with BRCA1/2 ...
Krogan, Nevan J, Tutuncuoglu, Beril
core  

BRIP-1 germline mutation and its role in colon cancer: presentation of two case reports and review of literature. [PDF]

, 2019
BackgroundHereditary colon cancer is characterized by the inheritance of an abnormal gene mutation which predisposes to malignancy. Recent advances in genomic medicine have identified mutations in "novel" genes as conferring an increased risk of ...
Ali, Mir, Chaudhary, Uzair, Delozier, Celia Dawn   +2 more
core  

Long term response on Regorafenib in non-V600E BRAF mutated colon cancer: a case report [PDF]

, 2019
Callebout, Eduard, Claes, Kathleen, De Man, Marc, Ferdinande, Liesbeth, Geboes, Karen, Laurent, Stéphanie, Moura Ribeiro, Suzane, Van der Meulen, Joni   +7 more
core   +2 more sources

Clinicopathological Features of Non-Small Cell Lung Carcinoma with BRAF Mutation. [PDF]

Curr Oncol, 2023
Ambrosini-Spaltro A, Rengucci C, Capelli L, Chiadini E, Calistri D, Bennati C, Cravero P, Limarzi F, Nosseir S, Panzacchi R, Valli M, Ulivi P, Rossi G.   +12 more
europepmc   +1 more source

BRAF V600E Mutation in Malignant Melanoma—A Romanian Research Experience

Medicina
Background and Objectives: The most common mutation in malignant melanoma (MM) is the single-point mutation of v-raf murine sarcoma viral oncogene homolog B1 (BRAF) oncogene.
Elena-Roxana Avădănei, Irina-Draga Căruntu, Irina Nucă, Raluca Balan, Ludmila Lozneanu, Simona-Eliza Giusca, Cornelia Amalinei   +6 more
doaj   +1 more source

Therapeutic strategies for BRAF mutation in non-small cell lung cancer: a review. [PDF]

Front Oncol, 2023
Puri M, Gawri K, Dawar R.
europepmc   +1 more source

BRAF Mutation Analysis [PDF]

, 2020
openaire   +1 more source

Prevalence and Impact of BRAF mutation in patients with concomitant papillary thyroid carcinoma and Hashimoto's thyroiditis: a systematic review with meta-analysis. [PDF]

Front Endocrinol (Lausanne), 2023
Janicki L, Patel A, Jendrzejewski J, Hellmann A.   +3 more
europepmc   +1 more source

Activating BRAF Mutation [PDF]

, 2020
openaire   +1 more source