Results 261 to 270 of about 183,340 (290)

Neural Organoids Protect Engineered Heart Tissues From Glucolipotoxicity by Transferring Versican in a Co‐Culture System

Cell Proliferation, EarlyView.
In this study, Bai et al. established a co‐culture system between neural organoids (NOs) and engineered heart tissues (EHTs) and demonstrated that NOs could secrete versican, which was absorbed by EHTs to ameliorate glucolipotoxicity. ABSTRACT Metabolic disorders could cause dysregulated glucose and lipid at the systemic level, but how inter‐tissue ...
Baochen Bai, Jiting Li, Ze Wang, Yuhan Yang, Jieqing He, Gonglie Chen, Yufan Zhang, Yan Qi, Zhongjun Wan, Lin Cai, Run Wang, Kai Wang, Dongyu Zhao, Jingzhong Zhang, Weihua Huang, Ronald X. Xu, Mingzhai Sun, Xiao Han, Yan Liu, Donghui Zhang, Wanying Zhu, Jian Liu, Yuxuan Guo   +22 more
wiley   +1 more source

Estimation of the Serum Levels of Brain-Derived Neurotrophic Factor (BDNF) and Interleukin-1β and Their Correlation With Clinical Severity in Depression Patients: A Case-Control Study. [PDF]

Cureus
Huded CB, Yedve S, Bagewadi HG, Satyanarayan N, Melkundi RS, Gogi PV, A S, Kallur R.   +7 more
europepmc   +1 more source

Myeloid PD‐1 Regulates Astrocyte Development and Leads to Active Behaviours

Cell Proliferation, EarlyView.
During early neurodevelopment, PD‐1 ablation in myeloid cells influences myeloid proliferation/differentiation and causes sustained astrocyte overproliferation. PD‐1f/f; LysM‐Cre mice showed elevated astrocyte gene expression and behavioural changes.
Jie Qin, Chong Wang, Sihan Li, Yanyan Wang, Tingting He, Jianwei Jiao, Fen Ji   +6 more
wiley   +1 more source

Modeling cerebral palsy in animals

Developmental Medicine &Child Neurology, EarlyView.
Abstract Advancements in the treatment of cerebral palsy depend on animal research. Yet, most animal models have not been fully evaluated for spasticity and dystonia using clinically relevant measures of altered tone or movement patterns, which form the basis for diagnosing people with the condition.
Katharina A. Quinlan, Emily J. Reedich, Elvia Mena Avila, Brendan C. Moline, Landon T. Genry, Megan R. Detloff, Benjamin R. Katholi, Deborah Gaebler‐Spira, Bhooma R. Aravamuthan   +8 more
wiley   +1 more source

Influence of Human Papillomavirus E6 Gene Mutation on Brain-Derived Neurotrophic Factor Regulation and Cell Proliferation in Cervical Neoplasia: Insights Into Molecular Mechanisms. [PDF]

Onco Targets Ther
Wei L, Yu Q, Chen SN.
europepmc   +1 more source

Psychiatric effects of GLP‐1 receptor agonists: A systematic review of emerging evidence

Diabetes, Obesity and Metabolism, EarlyView.
Abstract This systematic review examines the current literature on glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs)‐associated psychiatric manifestations, including depression, suicidality, eating disorders, substance use disorders (SUD) and schizophrenia spectrum disorders.
Brianna Sa, Anthony Maristany, Ashwin Subramaniam, Ryan Guillen, Brooke Buonocore, Audrey Smith, Sean E. Oldak, Vanessa Padilla   +7 more
wiley   +1 more source

Brain-Derived Neurotrophic Factor (BDNF) in Huntington's Disease: Neurobiology and Therapeutic Potential. [PDF]

Curr Neuropharmacol
Azman KF, Zakaria R.
europepmc   +1 more source

Brain-derived neurotrophic factor modulates immune reaction in mice with peripheral nerve xenotransplantation

, 2016
Yu Xi, Lu Liu, Zhihong Liu, T Yang, Xieyang Gong, Yubo Ning, Y Jiang   +6 more
openalex   +1 more source

Weight‐reducing treatments are associated with an improvement in depression, functional health status, and quality of life: A meta‐analysis of randomized controlled trials

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aim To assess whether there is a beneficial or detrimental effect of weight reduction on mental health. Materials and methods Meta‐analysis of randomized trials performed for weight loss, in which weight loss at endpoint was greater than 5% in the intervention arm and smaller than 5% in the control arm, obtained with any surgical, endoscopic ...
Giovanni Antonio Silverii, Matteo Monami, Francesco Rotella, Maurizio De Luca, Tommaso Viozzi, Rocco Barazzoni, Silvio Buscemi, Luca Busetto, Paolo Sbraccia, Edoardo Mannucci   +9 more
wiley   +1 more source

Investigating the Acute and Chronic Effects of Cardiovascular Exercise on Brain-Derived Neurotrophic Factor in Early Subacute Stroke. [PDF]

Neurorehabil Neural Repair
De Las Heras B, Rodrigues L, Cristini J, Yu E, Gan-Or Z, Arbour N, Thiel A, Tang A, Fung J, Eng JJ, Roig M.   +10 more
europepmc   +1 more source