Combination Therapy With Fingolimod and Neural Stem Cells Promotes Functional Myelination [PDF]
, 2019 Myelination, which occurs predominantly postnatally and continues throughout life, is important for proper neurologic function of the mammalian central nervous system (CNS).
Ciric, Bogoljub +7 more
core +1 more source
Enhancement of BDNF Concentration and Restoration of the Hypothalamic-Pituitary-Adrenal Axis Accompany Reduced Depressive-Like Behaviour in Stressed Ovariectomised Rats Treated with Either Tualang Honey or Estrogen [PDF]
, 2014 A possible interaction between glucocorticoids and estrogen-induced increases in brain-derived-neurotrophic factor (BDNF) expression in enhancing depressive-like behaviour has been documented.
Ahmad, Asma Hayati +4 more
core +3 more sources
Trajectory Networks and Their Topological Changes Induced by Geographical Infiltration [PDF]
arXiv, 2008 In this article we investigate the topological changes undergone by trajectory networks as a consequence of progressive geographical infiltration. Trajectory networks, a type of knitted network, are obtained by establishing paths between geographically distributed nodes while following an associated vector field.
arxiv
Design and Rationale of the Cognitive Intervention to Improve Memory in Heart Failure Patients Study [PDF]
, 2018 BACKGROUND: Memory loss is an independent predictor of mortality among heart failure patients. Twenty-three percent to 50% of heart failure patients have comorbid memory loss, but few interventions are available to treat the memory loss.
Dorsey, Susan G. +7 more
core +2 more sources
Human Genome data analyzed by an evolutionary method suggests a decrease in cerebral protein-synthesis rate as cause of schizophrenia and an increase as antipsychotic mechanism [PDF]
arXiv, 2001 The Human Genome Project (HGP) provides researchers with the data of nearly all human genes and the challenge to use this information for elucidating the etiology of common disorders. A secondary Darwinian method was applied to HGP and other research data to approximate and possibly unravel the etiology of schizophrenia.
arxiv
Depression, Neuroplasticity and Neurotrophic Factors [PDF]
, 2009 Depression is a common psychiatric disorder. There is still very little known about the neurobiological alterations that underlie the pathophysiology of depression.
Aslı Sarandöl +3 more
core
The Val66Met polymorphism in the BDNF gene is associated with epilepsy in fragile X syndrome [PDF]
, 2009 The Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene may modulate the epilepsy phenotype. We investigated the impact of polymorphisms in the BDNF gene on clinical features in fragile X syndrome (FXS).
Arvio, Maria +5 more
core +1 more source
Neurotrophin Signaling and Alzheimer’s Disease Neurodegeneration − Focus on BDNF/TrkB Signaling [PDF]
, 2013 Neurotrophins are small proteins vital for neuronal growth, differentiation, survival, and plasticity. Members of the mammalian neurotrophin family include nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and ...
Wong, Jenny
core +2 more sources
The Robust Kernel Association Test [PDF]
arXiv, 2019 Testing the association between SNP effects and a response is a common task. Such tests are often carried out through kernel machine methods based on least squares, such as the Sequence Kernel Association Test (SKAT). However, these least squares procedures assume a normally distributed response, which is often violated. Other robust procedures such as
arxiv
On Factor Left Prime Factorization Problems for Multivariate Polynomial Matrices [PDF]
arXiv, 2020 This paper is concerned with factor left prime factorization problems for multivariate polynomial matrices without full row rank. We propose a necessary and sufficient condition for the existence of factor left prime factorizations of a class of multivariate polynomial matrices, and then design an algorithm to compute all factor left prime ...
arxiv