Results 251 to 260 of about 2,520,525 (306)

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Cellular senescence in brain aging and neurodegeneration: from molecular mechanisms to translational opportunities. [PDF]

Front Cell Neurosci
Cantero-Fortiz Y, Butler C, Montalbán X, Boada M.   +3 more
europepmc   +1 more source

Race and Ethnicity, Hypertension, and Neuroimaging Markers of Brain Aging: A Causal Mediation Analysis in the HABS-HD Study. [PDF]

Neurology
Caunca M, Gutierrez S, Wheeler K, Braskie MN, Torres J, Yaffe K.   +5 more
europepmc   +1 more source

Astrocyte States in Brain Aging and Neurodegeneration: At the Crossroads of Senescence and Reactivity. [PDF]

Neurochem Res
Pacca-Corrêa JBL, Fernandes BM, Siqueira M, Schafbenker R, Baumart GJ, Damico IV, Gomes FCA, Matias I.   +7 more
europepmc   +1 more source

SIRT1 Activators as Geroprotective Agents in Brain Aging: Mechanisms and Therapeutic Potential. [PDF]

Neuromolecular Med
Alameen AAM, Al-Kuraishy HM, Al-Gareeb AI, Alexiou A, Papadakis M, Faheem SA, El-Saber Batiha G.   +6 more
europepmc   +1 more source

Region-specific transcriptional signatures of brain aging in the absence of neuropathology at the single-cell level. [PDF]

NPJ Aging
Mesecar ME, Duffy MF, Acri DJ, Ding J, Langston RG, Shah SI, Nalls MA, Reed X, Scholz SW, Thad Whitaker D, Auluck PK, Marenco S, DeCasien AR, Raphael Gibbs J, Cookson MR.   +14 more
europepmc   +1 more source

Mechanisms by Which Exercise Delays Brain Aging Through Regulation of the Mitochondrial Quality Control System. [PDF]

Biology (Basel)
Zhu X, Shi L, Dong Y, Sun Y, Jin Q.
europepmc   +1 more source

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Photobiomodulation for the aging brain

Ageing Research Reviews, 2021
Longevity is one of the great triumphs of humanity. Worldwide, the elderly is the fastest growing segment of the population. As a consequence, the number of cases of age-related cognitive decline and neurological diseases associated with aging, such as Alzheimer's and Parkinson's, has been increasing. Among the non-pharmacological interventions studied
F Gonzalez-Lima, Fabrizio dos Santos Cardoso, Sérgio Gomes da Silva   +2 more
exaly   +3 more sources

Aging and the brain

Current Opinion in Neurology, 1994
This review considers some of the changes that occur during aging in the mammalian central nervous system. We focus particularly on neurotransmitter systems, calcium homeostasis, synaptic transmission, oxidative metabolism, amyloid deposition, and other neuropathological and anatomical features.
J E, Goldman, N Y, Calingasan, G E, Gibson   +2 more
openaire   +2 more sources