Results 271 to 280 of about 2,520,525 (306)
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The New Brain Age

Neurology, 2022
The pandemic is transforming neurology. Long COVID will linger, neurologic diseases will increase, and technology, artificial intelligence, and new virtual worlds will usher a new age of the brain and new roles for neurologists. The pandemic has compelled international collaboration, greatly increased communications, and accelerated drug and vaccines ...
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Ischemia in Aged Brain

Gerontology, 2009
A 15-min complete cerebral ischemia, and repetitive ischemic insults of 15-min duration each cause changes in brain cortical glucose and energy metabolism which are similar in quality but different in quantity. Abnormalities in glycolytic flux, lactate production, cessation of oxidation and energy production were found to be more pronounced with ...
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Pathophysiology of Ageing Brain

Gerontology, 2009
Even in nonfamilial cases of dementia there is some evidence of a genetic factor. This may be linked to defective expression of neurofilament protein and also abnormal phosphorylation of cytoskeletal proteins. In this respect there may be a link with accumulation of tangles and amyloid which have some degree of homology.
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Estrogen and the aging brain

Maturitas, 2001
Evidence is presented indicating a role for estrogen in the function and maintenance of the aging brain. Based on complementary data that estrogen regulates the function of the immune--brain barrier, the hypothesis is presented that estrogen contributes to brain homeostasis via regulation of microglial activation, enabling immune-privileged status in ...
I, Silva, G, Mor, F, Naftolin
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Selenoproteins and the aging brain

Mechanisms of Ageing and Development, 2010
Selenium (Se) is an essential trace mineral mediating its biological function primarily through selenoproteins. Accumulated lines of evidence indicate important roles of selenoproteins in the maintenance of optimal brain functions via redox regulation.
Shu, Zhang   +2 more
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Brain Water and Aging

Journal of Gerontology, 1987
Brain water content and Na/K-ATPase activity have been compared in two groups of rats aged 60 ± 5 days (group I) and 630 ± 10 days (group II). In group II control animals, brain water content (p < 0.001) and Na/K-ATPase activity (p < 0.02) were found to be significantly reduced.
F, Cohadon, P, Desbordes
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NEUROIMAGING OF THE AGING BRAIN

Neurologic Clinics, 1998
Age-related white matter injury has been recognized increasingly with the improvement of brain imaging technology. Arteriosclerosis and venous collagenosis, which occur with aging, result in a spectrum of white matter changes that range from periventricular to subcortical and deep white matter hyperintensities best seen on T2 weighted magnetic ...
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Revitalizing the Aged Brain

Medical Clinics of North America, 2011
Optimal cognitive and emotional function is vital to independence, productivity, and quality of life. Cognitive impairment without dementia may be seen in 16% to 33% of adults older than 65 years, and is associated with significant emotional distress. Cognitive and emotional well-being are inextricably linked.
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Digitising brain age

The Lancet, 2022
David T, Jones   +2 more
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Design for an aging brain

Neurobiology of Aging, 2002
Vaillancourt and Newell (Neurobiol. of Aging 2001) show that although many aging systems decrease in complexity as anticipated by Lipsitz and Goldberger (JAMA 1992), other aging systems increase in complexity. Vaillancourt and Newell explain the discrepancy by proposing that systems with a point attractor decrease in complexity with age, whereas those ...
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