Results 51 to 60 of about 4,162,075 (205)

Biophysical and structural insights into the SCN4A E452K variant linked to myotonia and paramyotonia congenita

open access: yesScientific Reports
Myotonia and paramyotonia congenita (PC) are rare neuromuscular disorders characterized by muscle stiffness that intensifies in cold environments. These disorders are associated with variants in the SCN4A gene, that encodes the alpha subunit of the ...
Quentin Plumereau   +3 more
doaj   +1 more source

Hybrid Spectral Library Combining DIA-MS Data and a Targeted Virtual Library Substantially Deepens the Proteome Coverage

open access: yesiScience, 2020
Summary: Data-independent acquisition mass spectrometry (DIA-MS) is a powerful technique that enables relatively deep proteomic profiling with superior quantification reproducibility.
Ronghui Lou   +8 more
doaj   +1 more source

Single-cell RNA-sequencing identifies disease-associated oligodendrocytes in male APP NL-G-F and 5XFAD mice

open access: yesNature Communications, 2023
Oligodendrocytes have been increasingly shown to be involved in Alzheimer’s disease (AD). Here, the authors perform single-cell RNA-sequencing on APP NL-G-F mice and describe a disease-associated oligodendrocyte (DAO) population.
Hanseul Park   +6 more
doaj   +1 more source

Pheochromocytoma with Brain Metastasis: A Extremely Rare Case in Worldwide. [PDF]

open access: yes, 2018
Pheochromocytoma (PCC) is a neuroendocrine tumor that mainly arises from the medulla of the adrenal gland. Some PCCs become malignant and metastasize to other organs.
조윤성, 김세훈, 강석구
core   +1 more source

PENGARUH PENDEKATAN BRAIN-BASED TEACHING TERHADAP HASIL BELAJAR KIMIA

open access: yesJurnal Inovasi Pendidikan Kimia, 2015
This study aimed to determine the effect of inquiry method assisted e-module on the student learning outcomes of chemistry. Population in this study is XI grader in Senior High School (SHS) in Kudus, school year 2011/2012.
Hermawan Agung Prasetya   +1 more
doaj  

Addressing Math Deficits to Improve Chemistry Success [PDF]

open access: yesNonpartisan Education Review, 2020
The brain solves problems in structures termed "working memory." Between 2001 and 2010, cognitive experiments verified that at each step when solving a problem, working memory can hold only a few small elements of knowledge that are not well-memorized ...
Eric A. Nelson
doaj  

Wnt activation of immortalized brain endothelial cells as a tool for generating a standardized model of the blood brain barrier in vitro [PDF]

open access: yes, 2013
Reproducing the characteristics and the functional responses of the blood–brain barrier (BBB) in vitro represents an important task for the research community, and would be a critical biotechnological breakthrough.
Eleanna Papa (441409)   +52 more
core   +3 more sources

A Chronically Implantable Bidirectional Neural Interface for Non-human Primates

open access: yesFrontiers in Neuroscience, 2017
Optogenetics has potential applications in the study of epilepsy and neuroprostheses, and for studies on neural circuit dynamics. However, to achieve translation to clinical usage, optogenetic interfaces that are capable of chronic stimulation and ...
Misako Komatsu   +3 more
doaj   +1 more source

Graduate Study in Chemistry, The University of Texas at Austin, circa 1977

open access: yes, 1977
Table of Contents: Foreword (p. 3) -- The University (p. 4) -- The Austin Community (p. 6) -- Texas and Central Texas (p. 10) -- The Chemistry Department (p. 14) -- Research Specializations (p. 20-81) -- Analytical Chemistry (p.
Chemistry Department
core   +1 more source

Surface chemistry governs cellular tropism of nanoparticles in the brain

open access: yesNature Communications, 2017
There have been numerous attempts to develop nanomaterials to reach cells of the central nervous system for drug delivery. Here, the authors investigate the cellular fate of polymer-based nanoparticles with varying surface chemistries after ...
Eric Song   +9 more
doaj   +1 more source

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