Results 261 to 270 of about 166,999 (286)
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Current Alzheimer Research, 2007
Liver X receptors (LXRalpha and LXRbeta) are oxysterol receptors that function as master transcription factors mediating cholesterol homeostasis in the periphery. LXRs regulate the levels of the ABCA1 and ABCG1 cholesterol transporters as well as apolipoproteins (apoE and apoC) in various cells thereby affecting cholesterol transport and metabolism. In
Guoqing, Cao +3 more
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Liver X receptors (LXRalpha and LXRbeta) are oxysterol receptors that function as master transcription factors mediating cholesterol homeostasis in the periphery. LXRs regulate the levels of the ABCA1 and ABCG1 cholesterol transporters as well as apolipoproteins (apoE and apoC) in various cells thereby affecting cholesterol transport and metabolism. In
Guoqing, Cao +3 more
openaire +2 more sources
Quantifying brain cholesterol homeostasis
Nature Reviews Drug Discovery, 2022openaire +2 more sources
Brain and other central nervous system tumor statistics, 2021
Ca-A Cancer Journal for Clinicians, 2021Kimberly D Miller +2 more
exaly
Cholesterol homeostasis in the brain : importance of 24S-hydroxylation
1999Brain cholesterol is characterized by a very low turnover with very little exchange with lipoproteins in the circulation. We have investigated whether side chain-hydroxylated cholesterol species are important for elimination of cholesterol from the brain.
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Alterations of Brain Cholesterol Homeostasis in the Tg2576 Mouse Model of Alzheimer's Disease
2018Background: It is now well established that perturbations in cholesterol levels are crucial in the onset and development of Alzheimer’s disease (AD). Despite this evidence, scarce information is available about prospective alterations of proteins controlling brain cholesterol homeostasis in Alzheimer’s disease. Thus, the aim of this work was to analyze
Pallottini, Valentina, Segatto, Marco
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Amyloid beta accumulation in HIV-1 infected brain: the role of altered cholesterol homeostasis.
Clinical research in HIV/AIDSThe long-term survival of HIV-1 infected individuals credited to the availability and use of effective antiretroviral therapy (ART) is unfortunately now accompanied by an almost 50% prevalence of HIV-1 associated neurocognitive disorder (HAND).
Xuesong, Chen +2 more
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APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes
Nature, 2022Leyla Anne Akay +2 more
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Mechanisms and regulation of cholesterol homeostasis
Nature Reviews Molecular Cell Biology, 2019Jie Luo, Hongyuan Yang, Bao-Liang Song
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