Results 11 to 20 of about 3,348,173 (330)
Genome Biology, 2023 We define and identify a new class of control genes for next-generation sequencing called total RNA expression genes (TREGs), which correlate with total RNA abundance in cell types of different sizes and transcriptional activity. We provide a data-driven
Louise A. Huuki-Myers +6 more
doaj +1 more source
From early stress to 12-month development in very preterm infants: Preliminary findings on epigenetic mechanisms and brain growth [PDF]
, 2018 Very preterm (VPT) infants admitted to Neonatal Intensive Care Unit (NICU) are at risk for altered brain growth and less-than-optimal socio-emotional development.
Borgatti, R. +13 more
core +1 more source
Genome Biology, 2019 Background DNA methylation (DNAm) is a critical regulator of both development and cellular identity and shows unique patterns in neurons. To better characterize maturational changes in DNAm patterns in these cells, we profile the DNAm landscape at single-
Amanda J. Price +12 more
doaj +1 more source
Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD
Molecular Brain, 2023 Alzheimer’s disease (AD) is a neurodegenerative disease characterized by Aβ deposition, tauopathy, neuroinflammation, and impaired cognition. The recent identification of associations between protein kinases and AD pathology has spurred interest in ...
Hyun-ju Lee +5 more
doaj +1 more source
Characteristics and treatments of large cystic brain metastasis: radiosurgery and stereotactic aspiration. [PDF]
, 2015 Brain metastasis represents one of the most common causes of intracranial tumors in adults, and the incidence of brain metastasis continues to rise due to the increasing survival of cancer patients. Yet, the development of cystic brain metastasis remains
Cheok, Stephanie +11 more
core +1 more source
Laminar fMRI: applications for cognitive neuroscience [PDF]
, 2019 The cortex is a massively recurrent network, characterized by feedforward and feedback connections between brain areas as well as lateral connections within an area.
de Lange, Floris P. +3 more
core +2 more sources
THE PSYCHOMOTOR THEORY OF HUMAN MIND [PDF]
, 2007 This study presents a new theory to explain the neural origins of human mind. This is the psychomotor theory. The author briefly analyzed the historical development of the mind-brain theories.
TAN, Prof. Dr. Uner
core +1 more source
Human in vitro models for understanding mechanisms of autism spectrum disorder. [PDF]
, 2020 Early brain development is a critical epoch for the development of autism spectrum disorder (ASD). In vivo animal models have, until recently, been the principal tool used to study early brain development and the changes occurring in neurodevelopmental ...
Geschwind, Daniel H, Gordon, Aaron
core
BMC Genomics, 2019 Background RNA sequencing offers advantages over other quantification methods for microRNA (miRNA), yet numerous biases make reliable quantification challenging.
Carrie Wright +10 more
doaj +1 more source
Journal of Neuroinflammation, 2019 Background The FDA-approved small-molecule drug dasatinib is currently used as a treatment for chronic myeloid leukemia (CML). However, the effects of dasatinib on microglial and/or astrocytic neuroinflammatory responses and its mechanism of action have ...
Ka-Young Ryu +11 more
doaj +1 more source