Results 21 to 30 of about 3,343,469 (285)
Sexually size dimorphic brains and song complexity in passerine birds [PDF]
, 2004 Neural correlates of bird song involve the volume of particular song nuclei in the brain that govern song development, production, and perception. Intra- and interspecific variation in the volume of these song nuclei are associated with overall brain ...
Eens, Marcel +3 more
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Journal of Neuroinflammation, 2019 Background The FDA-approved small-molecule drug dasatinib is currently used as a treatment for chronic myeloid leukemia (CML). However, the effects of dasatinib on microglial and/or astrocytic neuroinflammatory responses and its mechanism of action have ...
Ka-Young Ryu +11 more
doaj +1 more source
Developmental expression of 4-repeat-Tau induces neuronal aneuploidy in Drosophila tauopathy models [PDF]
, 2017 Tau-mediated neurodegeneration in Alzheimer's disease and tauopathies is generally assumed to start in a normally developed brain. However, several lines of evidence suggest that impaired Tau isoform expression during development could affect mitosis and
Amouyel, Philippe +17 more
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Journal of Neuroinflammation, 2018 Background The FDA-approved small-molecule drug ibrutinib is an effective targeted therapy for patients with chronic lymphocytic leukemia (CLL). Ibrutinib inhibits Bruton’s tyrosine kinase (BTK), a kinase involved in B cell receptor signaling.
Hye Yeon Nam +8 more
doaj +1 more source
HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency. [PDF]
, 2017 Most studies of HIV latency focus on the peripheral population of resting memory T cells, but the brain also contains a distinct reservoir of HIV-infected cells in microglia, perivascular macrophages, and astrocytes.
Alvarez-Carbonell, David +4 more
core +1 more source
Scientific Reports, 2023 Memory compensation strategies serve an important role in everyday functioning, especially in the face of cognitive decline. Research on the external memory compensation strategies employed by older adults has focused almost entirely on non-digital tools.
Madeleine J. Radnan +3 more
doaj +1 more source
Barrier mechanisms in neonatal stroke. [PDF]
, 2014 Clinical data continue to reveal that the incidence of perinatal stroke is high, similar to that in the elderly. Perinatal stroke leads to significant morbidity and severe long-term neurological and cognitive deficits, including cerebral palsy ...
Chip, Sophorn +2 more
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The VEGF inhibitor vatalanib regulates AD pathology in 5xFAD mice
Molecular Brain, 2020 Alzheimer’s disease (AD) is a highly prevalent neurodegenerative disease characterized by Aβ accumulation and tau hyperphosphorylation. Epidemiological evidence for a negative correlation between cancer and AD has led to the proposed use of tyrosine ...
Seong Gak Jeon +4 more
doaj +1 more source
Scientific Reports, 2022 Human movements are spontaneously attracted to auditory rhythms, triggering an automatic activation of the motor system, a central phenomenon to music perception and production.
Olivia Morgan Lapenta +3 more
doaj +1 more source
The labial gene is required to terminate proliferation of identified neuroblasts in postembryonic development of the Drosophila brain [PDF]
, 2012 The developing brain of Drosophila has become a useful model for studying the molecular genetic mechanisms that give rise to the complex neuronal arrays that characterize higher brains in other animals including mammals.
Bello, B. C., Kuert, P. A., Reichert, H.
core +3 more sources