Results 221 to 230 of about 358,246 (264)
Some of the next articles are maybe not open access.
CARBOHYDRATE METABOLISM IN BRAIN DISEASE
A.M.A. Archives of Neurology & Psychiatry, 1954CLAUDE BERNARD'S experiments of a century ago stimulated interest in the relation between functions of the brain and glucose metabolism. Some authors, including Jelliffe,1have since reported metabolic abnormalities in multiple sclerosis; the reported changes consisted in a low fasting serum inorganic phosphorus3and a high fasting serum cholesterol ...
D H, HENNEMAN +3 more
openaire +2 more sources
Brain Iron Metabolism and CNS Diseases
2019Iron is the most abundant trace element in the human body. It is well known that iron is an important component of hemoglobin involved in the transport of oxygen. As a component of various enzymes, it participates in the tricarboxylic acid cycle and oxidative phosphorylation.
Anand, Thirupathi, Yan-Zhong, Chang
openaire +2 more sources
Brain cholesterol metabolism and neurologic disease
Neurology, 2008ABC= : ATP binding cassette; ABCA1= : ABC transporter protein family member A1; AD= : Alzheimer disease; apoE= : apolipoprotein E; APP= : amyloid precursor protein; ATP= : adenosine triphosphate; CoA= : coenzyme A; CYP= : cytochrome P; 7-DHC= : 7-dehydrocholesterol; ER= : endoplasmic reticulum; HD= : Huntington disease;
openaire +2 more sources
Carbohydrate Metabolism in Brain Disease
A.M.A. Archives of Internal Medicine, 1960Introduction Earlier communications from this laboratory reported abnormalities in carbohydrate metabolism in various psychotic states. 1,2 Among the most important of the changes noted in patients was an excessive rise in lactate and pyruvate after ingestion of glucose or fructose; similar changes in α-ketoglutarate and citrate have also been ...
openaire +1 more source
Metabolic Diseases of the Brain
2013Metabolic disorders are responsible for brain diseases causing abnormal growth and development. They are caused by genetically determined enzymatic defects in the metabolic pathways producing structurally defective protein. Enzymes are contained in the cellular organelles, and metabolic brain diseases can be categorized according to the most frequently
openaire +1 more source
Carbohydrate Metabolism in Brain Disease
A.M.A. Archives of Internal Medicine, 1957Earlier work has shown that patients with schizophrenic, manic-depressive, and involutional psychoses have a disorder of carbohydrate metabolism 1 that is indistinguishable from one exhibited by nonpsychotic patients with a chronic brain disease, i. e., multiple sclerosis.
M D, ALTSCHULE, P D, HOLLIDAY, M, VICTOR
openaire +2 more sources
Altered arginine metabolism in Alzheimer's disease brains
Neurobiology of Aging, 2014L-arginine is a semi-essential amino acid with a number of bioactive metabolites. Accumulating evidence suggests the implication of altered arginine metabolism in the pathogenesis of Alzheimer's disease (AD). The present study systematically compared the metabolic profile of L-arginine in the superior frontal gyrus, hippocampus, and cerebellum from AD (
Ping Liu +8 more
openaire +2 more sources
Degenerative and Metabolic Brain Diseases
2015Neurodegenerative diseases are rare in childhood. Most of them result from disturbances in the metabolism of energy, lipids, amino acids, or metals. Symptoms may not appear before childhood or adolescence, but some are fatal in utero or in the neonatal period; they form the core of this overview.
openaire +1 more source
Brain Iron Metabolism Dysfunction in Parkinson’s Disease
Molecular Neurobiology, 2016Dysfunction of iron metabolism, which includes its uptake, storage, and release, plays a key role in neurodegenerative disorders, including Parkinson's disease (PD), Alzheimer's disease, and Huntington's disease. Understanding how iron accumulates in the substantia nigra (SN) and why it specifically targets dopaminergic (DAergic) neurons is ...
Hong, Jiang +3 more
openaire +2 more sources
Journal of Neuroscience Research, 2001
AbstractThe potential of impairments in oxidative/energy metabolism to cause diseases of the brain had been proposed even before the major pathways of oxidative/energy metabolism were described. Deficiencies associated with disease are known in all the pathways of oxidative/energy metabolism and are associated with some of the most common disorders of ...
openaire +2 more sources
AbstractThe potential of impairments in oxidative/energy metabolism to cause diseases of the brain had been proposed even before the major pathways of oxidative/energy metabolism were described. Deficiencies associated with disease are known in all the pathways of oxidative/energy metabolism and are associated with some of the most common disorders of ...
openaire +2 more sources