Results 51 to 60 of about 12,998,191 (376)
Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer’s disease and track disease progression and cognitive decline [PDF]
, 2016 Acknowledgments We would like to gratefully acknowledge all donors and their families for the tissue provided for this study. Human tissue samples were supplied by the Brains for Dementia Research programme, jointly funded by Alzheimer’s Research UK, the
Cranston, Anna +5 more
core +3 more sources
Validation of Induced Microglia-Like Cells (iMG Cells) for Future Studies of Brain Diseases
Frontiers in Cellular Neuroscience, 2021 Microglia are the primary resident immune cells of the central nervous system that maintain physiological homeostasis in the brain and contribute to the pathogenesis of many psychiatric disorders and neurodegenerative diseases.
A. Banerjee +6 more
semanticscholar +1 more source
Cognitive Impairments in Ataxia-Telangiectasia
Pediatric Neurology Briefs, 2014 Investigators from Massachusetts General Hospital, Boston, and centers in Frankfurt, Germany, examined 22 patients with the classic phenotype of ataxia-telangiectasia for neurocognitive features, and compared patients with early stage cerebellar disease (
J Gordon Millichap, John J Millichap
doaj +1 more source
Nanozymes Regulate Redox Homeostasis in ROS-Related Inflammation
Frontiers in Chemistry, 2021 Reactive oxygen species (ROS), in moderate amounts, play an essential role in regulating different physiological functions in organisms. However, increased amounts of ROS may cause oxidative stress and damage to biomolecules, leading to a variety of ...
Qing Li +8 more
doaj +1 more source
New Promising Therapeutic Avenues of Curcumin in Brain Diseases
Molecules, 2021 Curcumin, the dietary polyphenol isolated from Curcuma longa (turmeric), is commonly used as an herb and spice worldwide. Because of its bio-pharmacological effects curcumin is also called “spice of life”, in fact it is recognized that curcumin possesses
T. Benameur +9 more
semanticscholar +1 more source
Music Affinity in Wolf-Hirschhorn Syndrome
Pediatric Neurology Briefs, 2014 Investigators at Nihon University School of Medicine, Tokyo, Japan, report two patients with Wolf-Hirschhorn syndrome (WHS) who have a strong affinity for music, not previously described as a feature of this syndrome.
J Gordon Millichap, John J Millichap
doaj +1 more source
Emerging roles of TRIM27 in cancer and other human diseases
Frontiers in Cell and Developmental Biology, 2022 As a member of the TRIM protein family, TRIM27 is a RING-mediated E3 ubiquitin ligase that can mark other proteins for degradation. Its ubiquitination targets include PTEN, IκBα and p53, which allows it to regulate many signaling pathways to exert its ...
Chengpeng Yu +12 more
doaj +1 more source
Brain MRI in Parkinson's disease [PDF]
Frontiers in Bioscience, 2014 In this review article, conventional brain MRI and advanced MRI techniques in Parkinson`s disease (PD) are discussed, with emphasis on clinical relevance. Conventional brain MRI sequences generally demonstrate limited abnormalities specific for PD and in clinical practice brain MRI is mainly used to exclude other pathology.
Meijer, F.J.A. +3 more
openaire +2 more sources
The roles of endoglin gene in cerebrovascular diseases. [PDF]
, 2017 Endoglin (ENG, also known as CD105) is a transforming growth factor β (TGFβ) associated receptor and is required for both vasculogenesis and angiogenesis.
Ma, Li, Su, Hua, Zhang, Rui, Zhu, Wan
core +2 more sources
Quantitative Imaging in Medicine and Surgery, 2021 Photoacoustic imaging (PAI) is an emerging imaging strategy with a unique combination of rich optical contrasts, high ultrasound spatial resolution, and deep penetration depth without ionizing radiation.
Ting Qiu +9 more
semanticscholar +1 more source