Results 51 to 60 of about 12,470,437 (381)

"It's a brain disease" [PDF]

open access: yesPsychiatric Services, 1997
T elling me that I have a brain disease and that I should take medication does not solve my problems. When I was first given the label of “psychotic,” I’m not sure it really mattered to me what had caused it. What I heard was you telling me that I had a chronic disease.
openaire   +3 more sources

RNAs in Brain and Heart Diseases [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
In the era of single-cell analysis, one always has to keep in mind the systemic nature of various diseases and how these diseases could be optimally studied. Comorbidities of the heart in neurological diseases as well as of the brain in cardiovascular diseases are prevalent, but how interactions in the brain–heart axis affect disease development and ...
Beis, Dimitris   +9 more
openaire   +4 more sources

Drug delivery in overcoming the blood-brain barrier: role of nasal mucosal grafting [PDF]

open access: yes, 2017
The blood–brain barrier (BBB) plays a fundamental role in protecting and maintaining the homeostasis of the brain. For this reason, drug delivery to the brain is much more difficult than that to other compartments of the body. In order to bypass or cross
Carafa, Maria   +5 more
core   +1 more source

Rapidly Progressing Neurocognitive Disorder in a Male with FXTAS and Alzheimer's Disease. [PDF]

open access: yes, 2020
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder that usually begins in the early 60s and affects carriers of premutation expansion (55-200 CGG repeats) of the fragile X mental retardation 1 (FMR1) gene.
Aydin, Elber Yuksel   +8 more
core   +2 more sources

Is Addiction a Brain Disease? [PDF]

open access: yesNeuroethics, 2016
Where does normal brain or psychological function end, and pathology begin? The line can be hard to discern, making disease sometimes a tricky word. In addiction, normal 'wanting' processes become distorted and excessive, according to the incentive-sensitization theory.
openaire   +3 more sources

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial [PDF]

open access: yes, 2019
Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy.
Abano, Nenette   +966 more
core   +5 more sources

The P2X7 Receptor: Central Hub of Brain Diseases

open access: yesFrontiers in Molecular Neuroscience, 2020
The P2X7 receptor is a cation channel activated by high concentrations of adenosine triphosphate (ATP). Upon long-term activation, it complexes with membrane proteins forming a wide pore that leads to cell death and increased release of ATP into the ...
Roberta Andrejew   +6 more
semanticscholar   +1 more source

A Reevaluation of Chitosan-Decorated Nanoparticles to Cross the Blood-Brain Barrier

open access: yesMembranes, 2020
The blood-brain barrier (BBB) is a sophisticated and very selective dynamic interface composed of endothelial cells expressing enzymes, transport systems, and receptors that regulate the passage of nutrients, ions, oxygen, and other essential molecules ...
Hernán Cortés   +11 more
doaj   +1 more source

The roles of endoglin gene in cerebrovascular diseases. [PDF]

open access: yes, 2017
Endoglin (ENG, also known as CD105) is a transforming growth factor β (TGFβ) associated receptor and is required for both vasculogenesis and angiogenesis.
Ma, Li, Su, Hua, Zhang, Rui, Zhu, Wan
core   +2 more sources

Nanozymes Regulate Redox Homeostasis in ROS-Related Inflammation

open access: yesFrontiers in Chemistry, 2021
Reactive oxygen species (ROS), in moderate amounts, play an essential role in regulating different physiological functions in organisms. However, increased amounts of ROS may cause oxidative stress and damage to biomolecules, leading to a variety of ...
Qing Li   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy