Results 61 to 70 of about 1,760,110 (357)
Neurosurgeon's Perspective on Neuroimaging for Headaches
Neurosurgeons at Washington University School of Medicine, St Louis, MO, address the proposed utility and negative impact of guidelines proposed by the American Headache Society (AHS), in conjunction with the Choosing Wisely initiative of the American ...
J Gordon Millichap, John J Millichap
doaj +1 more source
Plant-derived phytochemicals have gifted humans with vast therapeutic potentials. Yet, the unique features of the blood–brain barrier significantly limit their accession to the target tissue and thus clinical translation in brain disease treatment ...
Yang Liu+11 more
doaj +1 more source
Brain JNK and metabolic disease [PDF]
Obesity, which has long since reached epidemic proportions worldwide, is associated with long-term stress to a variety of organs and results in diseases including type 2 diabetes. In the brain, overnutrition induces hypothalamic stress associated with the activation of several signalling pathways, together with central insulin and leptin resistance ...
Rubén Nogueiras+2 more
openaire +3 more sources
Imaging Studies of Aging, Neurodegenerative Disease, and Alcoholism. [PDF]
Neurodegenerative diseases such as Alzheimers disease, disorders such as alcoholism, and the aging process can lead to impaired cognitive function and dementia.
Eberling, Jamie, JAGUST, William J
core
Deep Neural Network with l2-norm Unit for Brain Lesions Detection
Automated brain lesions detection is an important and very challenging clinical diagnostic task because the lesions have different sizes, shapes, contrasts, and locations.
B Menze+5 more
core +1 more source
Microglia-derived microvesicles affect microglia phenotype in glioma [PDF]
Extracellular-released vesicles (EVs), such as microvesicles (MV) and exosomes (Exo) provide a new type of inter-cellular communication, directly transferring a ready to use box of information, consisting of proteins, lipids and nucleic acids.
Alfonso Grimaldi+14 more
core +5 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Pediatric Migraine Prescription Patterns
Investigators at Boston Children's Hospital determined the migraine prescription patterns in 4839 patients, ages 2 to 17 years, treated over a 4-year period.
J Gordon Millichap, John J Millichap
doaj +1 more source
γδ T Cells in Brain Homeostasis and Diseases
γδ T cells are a distinct subset of T cells expressing γδ T cell receptor (TCR) rather than αβTCR. Since their discovery, the critical roles of γδ T cells in multiple physiological systems and diseases have been investigated.
Jang Hyun Park, In Kang, Heung Kyu Lee
doaj +1 more source