Results 61 to 70 of about 1,760,110 (357)

Neurosurgeon's Perspective on Neuroimaging for Headaches

open access: yesPediatric Neurology Briefs, 2014
Neurosurgeons at Washington University School of Medicine, St Louis, MO, address the proposed utility and negative impact of guidelines proposed by the American Headache Society (AHS), in conjunction with the Choosing Wisely initiative of the American ...
J Gordon Millichap, John J Millichap
doaj   +1 more source

The Phytochemical Potential for Brain Disease Therapy and the Possible Nanodelivery Solutions for Brain Access

open access: yesFrontiers in Oncology, 2022
Plant-derived phytochemicals have gifted humans with vast therapeutic potentials. Yet, the unique features of the blood–brain barrier significantly limit their accession to the target tissue and thus clinical translation in brain disease treatment ...
Yang Liu   +11 more
doaj   +1 more source

Brain JNK and metabolic disease [PDF]

open access: yesDiabetologia, 2020
Obesity, which has long since reached epidemic proportions worldwide, is associated with long-term stress to a variety of organs and results in diseases including type 2 diabetes. In the brain, overnutrition induces hypothalamic stress associated with the activation of several signalling pathways, together with central insulin and leptin resistance ...
Rubén Nogueiras   +2 more
openaire   +3 more sources

Imaging Studies of Aging, Neurodegenerative Disease, and Alcoholism. [PDF]

open access: yes, 1995
Neurodegenerative diseases such as Alzheimers disease, disorders such as alcoholism, and the aging process can lead to impaired cognitive function and dementia.
Eberling, Jamie, JAGUST, William J
core  

Deep Neural Network with l2-norm Unit for Brain Lesions Detection

open access: yes, 2017
Automated brain lesions detection is an important and very challenging clinical diagnostic task because the lesions have different sizes, shapes, contrasts, and locations.
B Menze   +5 more
core   +1 more source

Microglia-derived microvesicles affect microglia phenotype in glioma [PDF]

open access: yes, 2019
Extracellular-released vesicles (EVs), such as microvesicles (MV) and exosomes (Exo) provide a new type of inter-cellular communication, directly transferring a ready to use box of information, consisting of proteins, lipids and nucleic acids.
Alfonso Grimaldi   +14 more
core   +5 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Pediatric Migraine Prescription Patterns

open access: yesPediatric Neurology Briefs, 2014
Investigators at Boston Children's Hospital determined the migraine prescription patterns in 4839 patients, ages 2 to 17 years, treated over a 4-year period.
J Gordon Millichap, John J Millichap
doaj   +1 more source

γδ T Cells in Brain Homeostasis and Diseases

open access: yesFrontiers in Immunology, 2022
γδ T cells are a distinct subset of T cells expressing γδ T cell receptor (TCR) rather than αβTCR. Since their discovery, the critical roles of γδ T cells in multiple physiological systems and diseases have been investigated.
Jang Hyun Park, In Kang, Heung Kyu Lee
doaj   +1 more source

CT in small animal brain diseases [PDF]

open access: yes, 2013
C
Gielen, Ingrid   +2 more
core   +1 more source

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