Results 121 to 130 of about 283,910 (304)
Advanced Science, EarlyView.This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Sarah Rezapourdamanab +14 more
wiley +1 more source
Neuroinflammation and white matter alterations in obesity assessed by Diffusion Basis Spectrum Imaging [PDF]
, 2019 Human obesity is associated with low-grade chronic systemic inflammation, alterations in brain structure and function, and cognitive impairment. Rodent models of obesity show that high-calorie diets cause brain inflammation (neuroinflammation) in ...
Ances, Beau M +11 more
core +1 more source
Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants
Advanced Science, EarlyView.The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann +11 more
wiley +1 more source
Effects of Sesame Oil on Reducing Brain Injury and Edema in Experimental Model of Stroke in Rats
Journal of Mazandaran University of Medical Sciences, 2019 Background and purpose: Sesame oil (SO) is known to have antioxidant and anti-inflammatory properties and may produce protective effects against ischemic stroke-induced brain injuries.
Soheila Khedmati +3 more
doaj
Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound
Advanced Science, EarlyView.Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García +11 more
wiley +1 more source
AGING MEDICINE, EarlyView.This predictive model divides the low ASMI into three risk categories. Older adults in the low‐risk category, for whom SMM measurement is probably unnecessary. ABSTRACT Objectives Low skeletal muscle mass is associated with adverse clinical outcomes. Due to constraints related to cost and equipment availability, direct measurement of skeletal muscle ...
Minmin Chen +6 more
wiley +1 more source
KDLM: Lightweight Brain Tumor Segmentation via Knowledge Distillation
Advanced Intelligent Systems, EarlyView.A lightweight student network is designed, which is based on multiscale and multilevel feature fusion and combined with the residual channel attention mechanism to achieve efficient feature extraction and fusion with very few parameters. A dual‐teacher collaborative knowledge distillation framework is proposed.
Baotian Li +4 more
wiley +1 more source
RUDN Journal of Medicine, 2014 The aim of the study was to determine the role of fetal proteins AFP, CEA, CA 19-9, CA 125, CA 15-3, CA 72-4, CYFRA 21-1 in the pathogenesis of the development of clinically significant brain edema in patients with ischemic stroke. It is established that
A A Arkhipkin, O V Lyang, A G Kochetov
doaj
Swallowing and Communication in Cockayne Syndrome: Clinical Characteristics and Management
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Cockayne syndrome (CS) is an ultrarare genetic disorder associated with genes encoding proteins involved in DNA repair. The clinical course of CS involves neurodevelopmental and neurodegenerative features, including swallowing and communication impairments.
Abigail M. Spoden +2 more
wiley +1 more source
The 9th International RASopathies Symposium
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel +41 more
wiley +1 more source