Results 121 to 130 of about 1,911,944 (302)
Advanced Science, EarlyView.MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang +13 more
wiley +1 more source
Peritumoral edema at brain meningiomas
Acta Biomedica Scientifica, 2016 Among edema-producing neoplasms of central neural system, the meningiomas are unique. Meningiomas are histologically benign, slow growing and originate extracerebrally.
V. A. Byvaltsev +3 more
doaj +1 more source
Effect of Tranilast, an Anti-releasing Drug for Slow Reacting Substance, on Ischemic Brain Edema
, 1987 The effect of tranilast, an anti-releasing drug for slow reacting substance (SRS) on incomplete ischemia produced by a bilateral common carotid artery occlusion/recirculation model in the spontaneous hypertensive rat (SHR-SR) was investigated.
三宅, 仁志 +3 more
core
Brain edema in chronic hepatic encephalopathy [PDF]
, 2019 Brain edema is a common feature associated with hepatic encephalopathy (HE). In patients with acute HE, brain edema has been shown to play a crucial role in the associated neurological deterioration.
Taylor-Robinson, Simon D. +3 more
core +1 more source
Advanced Science, EarlyView.This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori +10 more
wiley +1 more source
Acta Radiologica Open, 2015 A 55-year-old woman underwent radiosurgery for a left cerebral hemisphere arteriovenous malformation (AVM) and developed radiation-induced necrosis causing a massive edema in the surrounding brain tissues. Despite various therapies, the edema expanded to
Yae Harada +10 more
doaj +1 more source
Advanced Science, EarlyView.HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li +8 more
wiley +1 more source
مجله علمی دانشگاه علوم پزشکی کردستان, 2021 Background and Aim: Increasing evidence has demonstrated that activation of peroxisome proliferator-activated receptor alpha (PPARα), which belongs to the nuclear receptor family of ligand-activated transcription factors, after cerebral ischemia exhibit ...
Hadi Vahidi +3 more
doaj
, 2007 Our knowledge regarding the influence of nanoparticles on brain function in vivo during normal or hyperthermic conditions is still lacking. Few reports indicate that when nanoparticles enter into the central nervous system (CNS) they may induce ...
Sharma, Aruna, +3 more
core +1 more source
Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source