Results 111 to 120 of about 188,500 (303)

Arterial Blood‐Mediated Deep‐Tissue Photoacoustic Oximetry

Advanced Science, EarlyView.
The arterial prior method (APM+) for photoacoustic oximetry is introduced, which leverages the high arterial blood oxygenation to calibrate the fluence at the artery and estimate the oxygenation of the surrounding tissue, thus circumventing the spectral coloring problem. APM+’s accuracy and consistency are shown in a series of phantom and in vivo human
Karteekeya Sastry, Junhao Zhu, Joshua Olick‐Gibson, Li Lin, Lei Li, Jigmi Basumatary, Yang Zhang, Lihong V. Wang   +7 more
wiley   +1 more source

Histopatologia do córtex motor cerebral em modelo de acidente vascular isquêmico em camundongo [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biologia Celular e do Desenvolvimento, Florianópolis, 2014.Modelo experimental de isquemia cerebral focal em camundongos C57/BL6 ...
Oliveira, Juçara Loli de
core  

Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation [PDF]

, 2012
Brain edema is the main cause of death from brain infarction. The polarized expression of the water channel protein aquaporin-4 (AQP4) on astroglial endfeet surrounding brain microvessels suggests a role in brain water balance.
Hannocks, Melanie-Jane, Engelhardt, Britta, Lydia Sorokin, Rüegg, Markus A, Britta Engelhardt, Zuber, Benoît, Sharang Ghavampour, Benoît Zuber, Lin, Shuo, Markus A. Rüegg, Melanie‐Jane Hannocks, Enzmann, Gaby U., Sorokin, Lydia, Steiner, Esther, Ghavampour, Sharang, Enzmann, Gaby U, Gaby U. Enzmann, Shuo Lin, Rüegg, Markus A., Esther Steiner   +19 more
core   +1 more source

EDEMA OF THE BRAIN IN THE INFECTIOUS DISEASES [PDF]

Journal of the American Medical Association, 1919
Little is to be found in the literature relative to edema of the brain in the infectious diseases as a clinical entity, and much less, therefore, if anything, as to edema as a clinical type of an infectious disease. We are all familiar with the occurrence of meningismus in acute diseases, and during the febrile stage are not surprised to have some ...
openaire   +2 more sources

Targeted Degradation of STING by a Neutrophil Membrane‐Coated Nanoplatform Suppresses Microglial Pyroptosis After Subarachnoid Hemorrhage

Advanced Science, EarlyView.
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang, Kaikun Yuan, Haoyu Zou, Hanfeng Qin, Jiale Liu, Jianda Sun, Feifan Zhang, Yuankui Wang, Tong Wang, Jiaxing Dai, Chunxu Li, Yichi Chen, Yingfeng Tu, Huaizhang Shi   +13 more
wiley   +1 more source

A Dual Parameter Synchronous Monitoring System of Brain Edema Based on the Reflection and Transmission Characteristics of Two-Port Test Network

IEEE Access, 2019
As a common secondary disease, edema after traumatic brain injury (TBI) can increase brain volume, resulting in elevated intracranial pressure (ICP), brain shift, and cerebral hernia, and can eventually lead to death.
Gen Li, Jingbo Chen, Shanshan Gu, Jun Yang, Yujie Chen, Shuanglin Zhao, Jia Xu, Zeling Bai, Jian Ren, Lin Xu, Mingsheng Chen, Mingxin Qin, Kwok Wa Leung, Jian Sun   +13 more
doaj   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Effect of fenofibrate on brain infarction, brain swelling and edema in focal-transient cerebral ischemia in rat

مجله علمی دانشگاه علوم پزشکی کردستان, 2021
Background and Aim: Increasing evidence has demonstrated that activation of peroxisome proliferator-activated receptor alpha (PPARα), which belongs to the nuclear receptor family of ligand-activated transcription factors, after cerebral ischemia exhibit ...
Hadi Vahidi, Shima Shahyad, Ali Noroozzadeh, Mohammad Taghi Mohammadi   +3 more
doaj  

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Brain Edema in Acute Liver Failure [PDF]

, 2010
Brain edema and the associated increase in intracranial pressure are potentially lethal complications of acute liver failure (ALF). Astrocyte swelling (cytotoxic edema) represents a significant component of the brain edema in ALF, and elevated blood and ...
Pichili V.B. Reddy, Reddy, Pichili V.B, Norenberg, Michael D, Kakulavarapu V. Rama Rao, Tong, Xiaoying, Michael D. Norenberg, Xiaoying Tong, Rama Rao, Kakulavarapu V   +7 more
core   +1 more source