Results 91 to 100 of about 283,910 (304)
Neutrophil depletion reduces edema formation and tissue loss following traumatic brain injury in mice [PDF]
, 2012 Background: Brain edema as a result of secondary injury following traumatic brain injury (TBI) is a major clinical concern. Neutrophils are known to cause increased vascular permeability leading to edema formation in peripheral tissue, but their role in ...
Anna Erlandsson +4 more
core +2 more sources
Advanced Science, EarlyView.This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source
Shiyan dongwu yu bijiao yixueObjective A novel compound based on near-infrared fluorescence (NIRF) probe was prepared to achieve dynamic monitoring of an inflammatory brain edema model in mice and real-time evaluation of therapeutic effects through in vivo imaging.
QIN Jing +4 more
doaj +1 more source
3D Convolutional Neural Networks for Brain Tumor Segmentation: A Comparison of Multi-resolution Architectures [PDF]
, 2017 This paper analyzes the use of 3D Convolutional Neural Networks for brain tumor segmentation in MR images. We address the problem using three different architectures that combine fine and coarse features to obtain the final segmentation. We compare three
Aduriz, Asier +3 more
core +3 more sources
Advanced Science, EarlyView.Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang +7 more
wiley +1 more source
The effect of dietary virgin olive oil on brain lipid levels and brain edema in rat stroke models [PDF]
, 2013 Background and Objective: Stroke is the third most common cause of death in industrialized countries after cardiovascular diseases and cancer. Despite numerous defenses, the brain is vulnerable to oxidative stress resulting from ischemia and reperfusion.
Asadi-Samani, Majid. +2 more
core
The blood labyrinthine barrier in the human normal and Meniere's disease macula utricle. [PDF]
, 2017 The ultrastructural organization of the blood labyrinthine barrier (BLB) was investigated in the human vestibular endorgan, the utricular macula, using postmortem specimens from individuals with documented normal auditory and vestibular function and ...
Ishiyama, Akira +4 more
core +2 more sources
PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
Advanced Science, EarlyView.This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source
Advanced Science, EarlyView.A brain‐adhesive sensor (B‐Sensor) was developed by integrating a self‐healing biodegradable elastomer, a tissue‐adhesive hydrogel, and molybdenum electrodes. The B‐Sensor adheres to brain tissue, conforms to cortical curvatures, and maintains stable electrical performance over the intended period for reliable recording of spatiotemporal brain activity
Heewon Choi +8 more
wiley +1 more source
Scientific Reports, 2017 Brain edema aggravates primary brain injury and increases its mortality rate after ischemic stroke. It is believed that normobaric oxygen therapy (NBO) may produce neuroprotective effects against ischemic stroke; however, reports have been controversial,
Elmira Pasban +2 more
doaj +1 more source