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Ocular Glymphatic System: Its Modulation and Role in Intraocular Tumors. [PDF]
Francis JH, Abramson DH.
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Lymphatic Endothelial Cells in Health and Disease. [PDF]
Tang D +5 more
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Lymphatic drainage of the brain
Experientia, 1968In krassem Gegensatz zur heute herrschenden Auffassung spielt eine Lymphdrainage beim Flussigkeitskreislauf des Gehirns eine ausschlaggebende Rolle. Werden die zervikalen Lymphbahnen verschlossen, so entsteht eine lymphostatische Enzephalopathie, welche u.a.
M, Földi, B, Csillik, O T, Zoltán
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Lymphatic drainage of the brain and the pathophysiology of neurological disease
Acta Neuropathologica, 2008There are no conventional lymphatics in the brain but physiological studies have revealed a substantial and immunologically significant lymphatic drainage from brain to cervical lymph nodes. Cerebrospinal fluid drains via the cribriform plate and nasal mucosa to cervical lymph nodes in rats and sheep and to a lesser extent in humans.
Roxana Carare
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A (delayed) history of the brain lymphatic system
Nature Medicine, 2019It has been only recently that scientists come to realize the existence of a lymphatic system within the central nervous system. However, an Italian anatomist had already found and described the system in fine detail over 200 years ago.
Stefano Sandrone +3 more
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Therapeutic Delivery to the Brain via the Lymphatic Vasculature
Nano Letters, 2020Targeted delivery of therapeutics to disease sites has been one of the biggest challenges in medicine, as it determines the treatment efficacy of virtually all chemical and biological drugs. Furthermore, it is particularly difficult to achieve for diseases in the brain because of an additional barrier compared to other organs, the blood-brain barrier ...
Pengfei Zhao +3 more
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The Brain and the Lymphatic System
2013The brain lacks a local lymphatic system, primarily due to the closed environment of the skull which sets strict requirements for control of fluid balance and intracranial pressure. Proper fluid and pressure balance are maintained in the brain through the unique systems of cerebrospinal and interstitial fluid as well as a tight coupling between these ...
Mark E. Wagshul, Miles Johnston
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