Results 121 to 130 of about 2,926,291 (344)

Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review

Advanced Robotics Research, EarlyView.
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley   +1 more source

Brain metastases in patients with low-grade endometrial carcinoma

Gynecologic Oncology Reports, 2018
Objective: To report characteristics of patients with low-grade endometrioid endometrial carcinoma (EC) who develop brain metastases. Methods: We retrospectively identified all patients treated at our institution for FIGO grades 1/2 EC from 1/2000–12 ...
Paulina Cybulska, Marina Stasenko, Raanan Alter, Vicky Makker, Karen A. Cadoo, Yukio Sonoda, Nadeem R. Abu-Rustum, Jennifer J. Mueller, Mario M. Leitao, Jr.   +8 more
doaj   +1 more source

Imaging of brain metastases

Surgical Neurology International, 2013
Imaging plays a key role in the diagnosis of central nervous system (CNS) metastasis. Imaging is used to detect metastases in patients with known malignancies and new neurological signs or symptoms, as well as to screen for CNS involvement in patients with known cancer.
Fink, Kathleen R., Fink, James R.
openaire   +2 more sources

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal, Milan Patra, Rianita Mondal, Shubhasis Haldar   +3 more
wiley   +1 more source

Brain metastases from renal cell carcinoma

, 2015
Brain metastasis is a major cause of morbidity and mortality in renal cancer patients. Treatment of metastatic renal cancer is difficult because most of RCCs are resistant to several therapeutic strategies: main studies support surgery as a therapeutic ...
FRATI, ALESSANDRO, PESCATORI, LORENZO, BRUNETTO, GIACOMA MARIA FLORIANA, D'ELIA, ALESSANDRO   +3 more
core  

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

MR determined brain metabolic pattern in patients with brain metastases and adolescents with low birth weight [PDF]

, 2007
The clinical applications of MRS have become a supplement to MR imaging (MRI) for diagnosis and treatment monitoring of several pathologies. In this thesis MR spectroscopy (MRS) has been used to assess brain metastases in adult cancer patients and ...
Sjøbakk, Torill Eidhammer
core  

Prognostic Value of Brain Metastasis Free Interval in Patients with Breast Cancer Brain Metastases

, 2019
Background: In patients with breast cancer brain metastases (BCBM), time between primary tumor diagnosis and appearance of brain metastases varies widely.
Claes, An, Claes, A., Smith, T.R., Broekman, M.L.D., Smith, Timothy R, Hulsbergen, A.F.C., Verhoeff, J.J.C., Lin, N.U., Lin, Nancy U, Kavouridis, V.K., Verhoeff, Joost J C, Hulsbergen, Alexander F C, Kavouridis, Vasileios, Broekman, Marike L D, Lamba, N., Lamba, Nayan   +15 more
core   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source