Results 181 to 190 of about 205,089 (292)

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

Tailored radiotherapy for brain metastases improves precision and outcomes. [PDF]

Discov Oncol
Bao J, Xu X, Wei S, Pan Z.
europepmc   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

Advanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju, Zhifang Liu, Xinran Gao, Wen Sun, Wei Fu, Yanfei Wang   +5 more
wiley   +1 more source

Characterisation and impact of intratumoural stroma in melanoma and carcinoma brain metastases. [PDF]

J Pathol Clin Res
Bandke D, Weis S, Gruber A, Noack P, Kalev O, Ornig K, Langer R.   +6 more
europepmc   +1 more source

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Adenosine Pathway Activation Defines Genetically Linked Immunosuppressive Subtypes in Solid Tumor Brain Metastases. [PDF]

Cancers (Basel)
Bauer A, Arndt A, Reichenbach L, Gebauer N, Müller M, Neumann C, Schulz C, Steinestel K, Heller R, Chteinberg E, Busch H, Riecke A, Künstner A, Witte H.   +13 more
europepmc   +1 more source

Multimodal imaging in an experimental rat model for brain metastasis [PDF]

, 2017
De Meulenaere, Valerie, De Wever, Olivier, Deblaere, Karel, Decrock, Elke, Descamps, Benedicte, Neyt, Sara, Vandeghinste, Bert, Vanhove, Christian   +7 more
core   +1 more source

Reduced CB1 Cannabinoid Receptor Expression in Alzheimer's Disease and Transgenic Mouse Models

AGING MEDICINE, EarlyView.
CB1 receptor (CB1R) expression was significantly reduced in the hippocampus, medial frontal gyrus, and superior temporal gyrus of Alzheimer's patients. CB1R levels negatively correlated with amyloid‐β and tau pathology. In addition, CB1R expression was also reduced in the cortex of 5xFAD mice and in the hippocampus of Tg4‐42 mice.
Nike von Borcke, Amrei Vivian Purwien, Annik Steiert, Henrike Hasecke, Yvonne Bouter   +4 more
wiley   +1 more source

The role of miRNAs in the development of brain metastases originating from lung adenocarcinoma. [PDF]

Front Genet
Torner B, Klekner Á, Balogh I, Penyige A, Géczi D, Gáspár T, Geszti G, Birkó Z.   +7 more
europepmc   +1 more source

Bona Fide Intersegmental Plane Hepatectomy Along the Glissonean Branches (BIPHG)

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT This review traces the author's personal journey over three decades in the evolution of liver resection techniques, culminating in the proposal of the Bona Fide Intersegmental Plane Hepatectomy Along Glissonean Branches (BIPHG). Beginning with pioneering experiences in laparoscopic and robotic liver surgeries, the author highlights key ...
Go Wakabayashi, Taiga Wakabayashi
wiley   +1 more source