Results 171 to 180 of about 205,089 (292)

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Integrating multimodal management and molecular profiling in a patient with BRAF V600E-positive melanoma and brain metastases. [PDF]

CA Cancer J Clin
Gritsch D, Fadden RM, Mahar MK, Khandsekar MJ, Oh KS, Cahil DP, Dunn GP, Sullivan RJ, Brastianos PK.   +8 more
europepmc   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

Evaluating the Translation Value of Two <i>In Vivo</i> Models for Breast Cancer Brain Metastases. [PDF]

Cancers (Basel)
Cold S, Alfsen MZ, Halgirsson B, Jorgensen MN, Hald J, Nielsen CH, Kjaer A, Kristensen LK, Engel TB.   +8 more
europepmc   +1 more source

Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang, Ning Lu, Zhuo Yan, Luyi Ye, Luyao Bai, Shanshan Yuan, Yuting Zhu, Yiru Xiong, Yongheng Bai, Yaping Chen, Junjie Deng   +10 more
wiley   +1 more source

Editorial: Brain Metastases (Secondary Brain Tumor). [PDF]

Cancers (Basel)
Shida D.
europepmc   +1 more source

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

Advanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole, Andrew Lai, Alexander Quinn, Marianne Gillard, Dominic Guanzon, Katherin Scholz‐Romero, Alexis Salas‐Burgos, Bastián Lillo Dapremont, Rohan Lourie, Naven Chetty, Richard Lobb, Kate Beecher, Amy E. McCart Reed, Kaltin Ferguson, Biao Sun, Yaowu He, John D. Hooper, Carlos Salomon   +17 more
wiley   +1 more source

Circulating microRNAs as Biomarkers of Brain Metastases in Lung Cancer: A Pilot Study. [PDF]

J Clin Med
Marschollek K, Powierża M, Kujawa D, Kosacka M, Majchrzak M, Brzecka-Bonnaud A, Kowal A, Budrewicz S, Łaczmański Ł, Pokryszko-Dragan A.   +9 more
europepmc   +1 more source

A High‐Throughput Live Imaging Platform to Investigate Circuit‐Dependent Regulation of Circadian Rhythms in Brain Tissue

Advanced Science, EarlyView.
Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari, Natalie Ness, Julieta Acosta, Marco Brancaccio   +3 more
wiley   +1 more source

Brain Metastases in Diffuse Pleural Mesothelioma: Clinical, Histologic, and Molecular Correlates. [PDF]

JTO Clin Res Rep
Ocejo A, Wilhem C, Bodd FM, Arfe A, Zauderer MG, Iqbal A, Eng J, Yu Y, Budhu JA, Schefflein J, Young R, Kris MG, Moss NS, Bou-Nassif R, Simone CB, Adusumilli PS, Sauter JL, Offin M.   +17 more
europepmc   +1 more source