Results 151 to 160 of about 1,871,454 (260)

Surgical Management of Recurrent Brain Metastases: A Review. [PDF]

Cancers (Basel)
Sampson JW, Goethe EA, Ferguson SD.
europepmc   +1 more source

Comparative analysis of TP53 gene in Tupaia belangeri subspecies (Tupaia belangeri yaoshanensis vs. Tupaia belangeri chinensis) and identification of mutations in spontaneous tumor cases

Animal Models and Experimental Medicine, EarlyView.
This study provides the first evidence of natural TP53 variation between tree shrew subspecies and identifies somatic TP53 mutations in spontaneous tree shrew sarcomas. The high structural and functional conservation of tree shrew p53 with humans supports its utility as a relevant model for TP53‐related cancer research.
Yingying Cao, Haibo Tang, Liang Liang, Jing Leng, Weijian Huang   +4 more
wiley   +1 more source

Antibody-drug conjugates in brain metastases: evidence outpacing trial design. [PDF]

ESMO Open
Sarfraz Z, Tarantino P, Mahtani R, Ahluwalia MS.   +3 more
europepmc   +1 more source

Patterns of CNS metastases in breast cancer patients

, 2016
In den letzten Jahren wurde eine steigende Inzidenz der ZNS-Metastasen beim Mammakarzinom verzeichnet. Diese sind ein limitierender Faktor für die Lebensqualität betroffener Patientinnen und mit einer eingeschränkten Prognose verbunden.
Scriba, Verena
core  

Zebrafish xenograft models as a fast platform for metastasis diagnosis and cisplatin response of head and neck squamous cell carcinoma

Animal Models and Experimental Medicine, EarlyView.
A zebrafish xenograft model accurately distinguishes metastatic from non‐metastatic HNSCC and recapitulates cisplatin sensitivity/resistance patterns. Using patient‐derived tumors, it predicts individual therapeutic responses, offering a rapid, clinically applicable platform for guiding personalized treatment. Abstract Background Head and neck squamous
Lu Chen, Shu Sun, Yujia Liu, Liehao Jiang, Cuiyun Wu, Ting Liu, Yujiao Zhao, Yuwei Liu, Lu Liu, Qi Wang, Xiaowei Zheng, Ping Huang   +11 more
wiley   +1 more source

Clinically actionable genomic alterations in breast cancer brain metastases. [PDF]

ESMO Open
Griguolo G, Collesei A, Lazzarini E, Bottosso M, Dieci MV, Fineberg S, Bauchet L, Landa G, Miglietta F, Jacob J, Rigau V, La Commare M, Trovò L, Fassan M, Jacot W, Dei Tos AP, Indraccolo S, Darlix A, Guarneri V.   +18 more
europepmc   +1 more source

Growth Differentiation Factor 15 as a Cerebrospinal Fluid Biomarker for the Diagnosis and Prognosis of Leptomeningeal Metastasis

Annals of Neurology, EarlyView.
Objective As leptomeningeal metastasis (LM) has a poor prognosis, reliable cerebrospinal fluid (CSF) diagnostic biomarkers are urgently needed. This study evaluated the diagnostic value of CSF growth differentiation factor 15 (GDF15) in LM from lung adenocarcinoma (LUAD) and breast cancer (BC).
Haoyu Ruan, Jie Li, Fuhai Wang, Lei Zhang, Jie Luo, Yuan Mu, Ting Wang, Yuqing Wu, Jingping Liu, Yunyun Ning, Xuan Deng, Ming Guan, Jian Xu   +12 more
wiley   +1 more source

Nanofabricated Biomaterials Model Tumor Extracellular Matrix Topography

Advanced NanoBiomed Research, EarlyView.
The unique structure and composition of the tumor microenvironment and its associated extracellular matrix (ECM) exert profound effects on cancer cell behavior that are difficult to model in vitro. This perspective discusses the utility of nanofabricated biosubstrates, such as the novel collagen‐coated nanogrooved array, for recapitulating the ...
Vic Zamloot, JinSeok Park
wiley   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Stereotactic Radiosurgery for Thalamic Brain Metastases: A Retrospective Analysis and Literature Review. [PDF]

Neurosurg Pract
Kattaa AH, Persad AR, Harary PM, Kassu R, Izhar M, Guru S, Akhavan-Sigari A, Purger DA, Hori YS, Ustrzynski L, Emrich SC, Tayag A, Gu X, Wang L, Pollom EL, Soltys SG, Park DJ, Chang SD.   +17 more
europepmc   +1 more source