Results 141 to 150 of about 39,896 (297)
Multiscale Comparative Analyses of OVB-Organoids and Cerebral Organoids
CellsOrganoid technology is critical for studying human brain development, but existing single-organoid culture systems fail to simulate inter-organ interactions (e.g., optic vesicle–brain) in embryogenesis.
Jingyi Yang +3 more
doaj +1 more source
Zika virus has oncolytic activity against glioblastoma stem cells [PDF]
, 2017 Diamond, Michael S +2 more
core +2 more sources
Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation
Advanced Science, EarlyView.This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar +10 more
wiley +1 more source
Bioengineering & Translational MedicineSelf‐organizing brain organoids provide a promising tool for studying human development and disease. Here we created human forebrain organoids with stable and homogeneous expression of channelrhodopsin‐2 (ChR2) by generating AAVS1 safe harbor locus ...
Soojung Hong +4 more
doaj +1 more source
Neural Regeneration ResearchThe brain is the most complex human organ, and commonly used models, such as two-dimensional-cell cultures and animal brains, often lack the sophistication needed to accurately use in research.
Raquel Coronel +10 more
doaj +1 more source
Bioengineering of brain organoids
, 2023 Understanding the human brain is an exciting challenge in particular for scientists. Studying the behavior of the human brain can lead to understanding the causes of several diseases and delineate a path to find possible cures. The use of animal models has helped scientist historically to meet these goals; however, there are important differences ...
openaire +1 more source
Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics
Advanced Electronic Materials, EarlyView.Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim +7 more
wiley +1 more source
Illuminating the Intracellular World: Breakthroughs in Nanoscale Optoelectronics
Advanced Electronic Materials, EarlyView.This perspective explores optoelectronic biointerfaces spanning macroscale flexible devices to nanoscale intracellular systems, emphasizing their integration across dimensions. It examines capacitive, Faradaic, and photothermal mechanisms that enable light‐driven control of cellular activity and highlights key material and design challenges in ...
Tania Assaf, Menahem Y. Rotenberg
wiley +1 more source
Brain organoid maturation and implantation integration based on electrical signals input
Journal of Advanced ResearchIntroduction: Brain organoids are believed to be able to regenerate impaired neural circuits and reinstate brain functionality. The neuronal activity of organoids is considered a crucial factor for restoring host function after implantation. However, the
Xiao-Hong Li +11 more
doaj +1 more source
Material Strategies for Stimulation and Recording in Neural Biocomputing Platforms
Advanced Electronic Materials, EarlyView.Material strategies enabling stimulation and recording are central to neural biocomputing systems. This review examines how electronic materials govern the encoding of inputs and decoding of outputs in living neural networks. Advances in electrical, optical, and multimodal interfaces highlight emerging design principles for biocomputing platforms ...
Sehong Kang +5 more
wiley +1 more source