Results 41 to 50 of about 933,949 (357)

Efficient generation of germline chimeras in a non-rodent species using rabbit induced pluripotent stem cells

Nature Communications
Pluripotent stem cells have long been used to produce knockout mice via germline chimera technology. However, aside from the rat, this approach has not been successfully applied to other mammals.
Hong-Thu Pham, Florence Perold, Yannicke Pijoff, Nathalie Doerflinger, Sylvie Rival-Gervier, Maëlle Givelet, Anaïs Moulin, Manon Ressaire, Emilie Da Silva Fernandes, Valeska Bidault, Luc Jouneau, Véronique Duranthon, Florence Wianny, Bertrand Pain, Ingrid Plotton, Thierry Joly, Marielle Afanassieff, Pierre Savatier, Nathalie Beaujean   +18 more
doaj   +1 more source

Astroglial Control of the Antidepressant-Like Effects of Prefrontal Cortex Deep Brain Stimulation

EBioMedicine, 2015
Although deep brain stimulation (DBS) shows promising efficacy as a therapy for intractable depression, the neurobiological bases underlying its therapeutic action remain largely unknown.
A. Etiévant, C. Oosterhof, C. Bétry, E. Abrial, M. Novo-Perez, R. Rovera, H. Scarna, C. Devader, J. Mazella, G. Wegener, C. Sánchez, O. Dkhissi-Benyahya, C. Gronfier, V. Coizet, J.M. Beaulieu, P. Blier, G. Lucas, N. Haddjeri   +17 more
doaj   +1 more source

Efficient generation of neural stem cell-like cells from adult human bone marrow stromal cells [PDF]

, 2004
Clonogenic neural stem cells (NSCs) are self-renewing cells that maintain the capacity to differentiate into brain-specific cell types, and may also replace or repair diseased brain tissue. NSCs can be directly isolated from fetal or adult nervous tissue,
Boehm, Bernhard O., Brenner, Rolf, Fiedler, Jörg, Gastl, Regina, Hermann, Andreas, Lerche, Holger, Liebau, Stefan, Maisel, Martina, Popa, M. Oana, Schwarz, Johannes, Storch, Alexander   +10 more
core  

Semi-Automatic 3-D Segmentation of Anatomical Structures of Brain MRI Volumes using Graph Cuts [PDF]

, 2006
We present a semi-automatic segmentation technique of the anatomical structures of the brain: cerebrum, cerebellum, and brain stem. The method uses graph cuts segmentation with an anatomic template for initialization.
Doan, H., Fang, T., Slabaugh, G. G., Unal, G. B.   +3 more
core   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Morphological characteristics of lateral branches of human basilar artery [PDF]

Vojnosanitetski Pregled, 2018
Background/Aim. Lateral branches of basilar artery mostly supply pons and cerebellum. The aim of this study was to determine the morphological characteristics of lateral branches and side branches of the individual lateral branches of human basilar ...
Gajanin Vesna, Sladojević Igor, Šarović-Vukajlović Mirka, Gajanin Radoslav, Ninković-Baroš Đuka, Krivokuća Božo   +5 more
doaj   +1 more source

Acute brain stem vertigo without neurological deficits

BLDE University Journal of Health Sciences, 2021
An infarct at the brain stem or cerebellum is rarely associated with vertigo without any other localizing clinical features. Stroke at the posterior circulation of the brain may cause spontaneous vertigo and imbalance.
Santosh Kumar Swain
doaj   +1 more source

Overexpression of Large-Conductance Calcium-Activated Potassium Channels in Human Glioblastoma Stem-Like Cells and Their Role in Cell Migration [PDF]

, 2017
Glioblastomas (GBMs) are brain tumors characterized by diffuse invasion of cancer cells into the healthy brain parenchyma, and establishment of secondary foci. GBM cells abundantly express large-conductance, calcium-activated potassium (BK) channels that
Abdullaev, Bao, Bednarczyk, Beier, Brenner, Brescia, Buttigieg, Calogero, Catacuzzeno, Catacuzzeno, Catacuzzeno, Catacuzzeno, Chen, Choy, Cuddapah, Eckel-Passow, Edalat, Eskandari, Fioretti, Fioretti, Gu, Holland, Inoue, Kyle, Liu, Maher, Maugeri-Saccà, Maugeri-Saccà, McFerrin, Meera, Park, Ransom, Ruggieri, Sforna, Sforna, Shruti, Siemen, Sontheimer, Soria, Soroceanu, Steinle, Torres, Turner, Wang, Weaver, Weiger, Wondergem, Wu, Yu, Zhang   +49 more
core   +1 more source

Pediatric brain stem gliomas [PDF]

Cancer, 1980
Sixty-two pediatric patients with brain stem glioma diagnosed between 1964 and 1978 have been reviewed. Posterior fossa eploration was performed on 53% of the patients. Pathology was obtained by biopsy in 58% of those explored. Fifty-four patients had definitive radiation therapy with a median dose of 5000 rads. The actuarial five-year survival for the
P, Littman, P, Jarrett, L T, Bilaniuk, L B, Rorke, R A, Zimmerman, D A, Bruce, S C, Carabell, L, Schut   +7 more
openaire   +2 more sources

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source