Results 21 to 30 of about 831,573 (301)
Generation of B-cell-based cellular vaccine for cancer in murine models
STAR Protocols, 2023 Summary: A B-cell-based cellular vaccine (BVax), produced from 4-1BBL+ B cells, can select tumor-specific B cells that, upon ex vivo culture, can generate tumor-specific antibodies and activate T cells.
David Hou +2 more
doaj +1 more source
Current Limitations of Intraoperative Ultrasound in Brain Tumor Surgery
Frontiers in Oncology, 2021 While benefits of intraoperative ultrasound (IOUS) have been frequently described, data on IOUS limitations are relatively sparse. Suboptimal ultrasound imaging of some pathologies, various types of ultrasound artifacts, challenging patient positioning ...
A. Šteňo +5 more
semanticscholar +1 more source
Immune Microenvironment Landscape in CNS Tumors and Role in Responses to Immunotherapy
Cells, 2021 Despite the important evolution of immunotherapeutic agents, brain tumors remain, in general, refractory to immune therapeutics. Recent discoveries have revealed that the glioma microenvironment includes a wide variety of immune cells in various states ...
Hinda Najem +2 more
doaj +1 more source
Induction and Characterization of Human Glioma Clones With Different Radiosensitivities
Neoplasia: An International Journal for Oncology Research, 1999 To facilitate investigation of the molecular mechanisms of tumor cell radiosensitivities, we have generated a set of clones with different radiosensitivities from a human glioma cell line U-251 MG-Ho.
Jingli Wang +7 more
doaj +1 more source
Surgical Management of Giant Prolactinomas: A Descriptive Study
International Journal of Endocrinology, 2023 Introduction. Giant prolactinoma (GP) is a rare pituitary lactotropic cell tumor larger than 4 cm in its widest dimension, and is less likely than a smaller prolactinoma to achieve prolactin normalization on dopamine agonist (DA) monotherapy.
Michelle D. Lundholm +5 more
doaj +1 more source
MMP14 as a novel downstream target of VEGFR2 in migratory glioma-tropic neural stem cells
Stem Cell Research, 2015 Neural stem cell (NSC)-based carriers have been presented as promising therapeutic tools for the treatment of infiltrative brain tumors due to their intrinsic tumor homing property.
Nikita G. Alexiades +11 more
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Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas
Nature Communications, 2023 Hedgehog signaling mediates embryologic development of the central nervous system and other tissues and is frequently hijacked by neoplasia to facilitate uncontrolled cellular proliferation.
Mark W. Youngblood +36 more
doaj +1 more source
History of brain tumor surgery – A global and Indian perspective
Archives of Medicine and Health Sciences, 2021 Brain tumor surgery has grown exponentially in the last century, aided by sophistication, globalization, and training initiatives. With progress in cerebral localization, antisepsis, anesthesia, and hemostasis, brain surgery took off in a cautious manner
P Shah Shreykumar +4 more
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Detection of Hypoxia in Human Brain Tumor Xenografts Using a Modified Comet Assay
Neoplasia: An International Journal for Oncology Research, 2003 We used the standard comet assay successfully to generate in vitro dose-response curves under oxic and hypoxic conditions. We then made mixtures of cells that had been irradiated with 3 and 9 Gy of X-rays to simulate two subpopulations in a tumor, but ...
Jingli Wang +8 more
doaj +1 more source
Neoplasia: An International Journal for Oncology Research, 2008 Neurofibromatosis type 2 (NF2) is an autosomal dominant disorder characterized by the occurrence of schwannomas and meningiomas. Several studies have examined the ability of the NF2 gene product, merlin, to function as a tumor suppressor in diverse cell ...
Katherine Striedinger +5 more
doaj +1 more source