Results 31 to 40 of about 831,573 (301)
Frontiers in Cellular Neuroscience, 2021 According to classical dogma, the central nervous system (CNS) is defined as an immune privileged space. The basis of this theory was rooted in an incomplete understanding of the CNS microenvironment, however, recent advances such as the identification ...
Dana Mitchell +4 more
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Anxiety in the preoperative phase of awake brain tumor surgery
Clinical Neurology and Neurosurgery, 2017 Pierre Robe +2 more
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Killing of Brain Tumor Cells by Hypoxia-Responsive Element Mediated Expression of BAX
Neoplasia: An International Journal for Oncology Research, 1999 The presence of radioresistant hypoxic cells in human brain tumors limits the overall effectiveness of conventional fractionated radiation therapy. Tumor-specific therapies that target hypoxic cells are clearly needed. We have investigated the expression
Hangjun Ruan +5 more
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Viruses, 2015 Oncolytic virotherapy for cancer is an innovative therapeutic option where the ability of a virus to promote cell lysis is harnessed and reprogrammed to selectively destroy cancer cells.
Janice Kim +3 more
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Cancer Cell International, 2022 Introduction The importance of fatty acid oxidation (FAO) in the bioenergetics of glioblastoma (GBM) is being realized. Etomoxir (ETO), a carnitine palmitoyltransferase 1 (CPT1) inhibitor exerts cytotoxic effects in GBM, which involve interrupting the ...
Jin-Kyoung Shim +15 more
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F1000Research, 2022 Median survival of patients with glioblastoma (GBM) treated with standard of care which consists of maximal safe resection of the contrast-enhancing portion of the tumor followed by radiation therapy with concomitant adjuvant temozolomide (TMZ) remains ...
Amy B Heimberger +9 more
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A Hypoxia-Regulated Adeno-Associated Virus Vector for Cancer-Specific Gene Therapy
Neoplasia: An International Journal for Oncology Research, 2001 The presence of hypoxic cells in human brain tumors is an important factor leading to resistance to radiation therapy. However, this physiological difference between normal tissues and tumors also provides the potential for designing cancer-specific gene
Hangjun Ruan +5 more
doaj +1 more source
5-Aminolevulinic acid fluorescence guided resection of malignant glioma: Hong Kong experience
Asian Journal of Surgery, 2018 Summary: Background: 5-Aminolevulinic Acid (5-ALA) induced fluorescence is useful in guiding glioma resection. The extent of 5-ALA accumulation is beyond gadolinium contrast enhancement.1,2 Supratotal resection may be achieved, potentially granting ...
Danny Tat Ming Chan +2 more
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Journal of Visualized Experiments, 2020 Phantoms are essential tools for clinical training, surgical planning and the development of novel medical devices. However, it is challenging to create anatomically accurate head phantoms with realistic brain imaging properties because standard ...
Eleanor C. Mackle +7 more
semanticscholar +1 more source
Notch Activation Is Associated with Tetraploidy and Enhanced Chromosomal Instability in Meningiomas
Neoplasia: An International Journal for Oncology Research, 2008 The Notch signaling cascade is deregulated in diverse cancer types. Specific Notch function in cancer is dependent on the cellular context, the particular homologs expressed, and cross-talk with other signaling pathways.
Gilson S. Baia +5 more
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