Results 91 to 100 of about 214,971 (307)

Novel Approach to Elucidate Human Baroreflex Regulation at the Brainstem Level: Pharmacological Testing During fMRI

Frontiers in Neuroscience, 2019
Introduction: Brainstem nuclei govern the arterial baroreflex, which is crucial for heart rate and blood pressure control. Yet, brainstem function is difficult to explore in living humans and is therefore mostly studied using animal models or postmortem ...
Darius A. Gerlach, Jorge Manuel, Alex Hoff, Hendrik Kronsbein, Hendrik Kronsbein, Fabian Hoffmann, Fabian Hoffmann, Karsten Heusser, Heimo Ehmke, André Diedrich, Jens Jordan, Jens Tank, Florian Beissner   +12 more
doaj   +1 more source

“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez, Carmen Espejo, Georgina Arrambide, Mireia Castillo, Marta Rodriguez, Helena Ariño, Iker Elosua, Carmen Tur, Angela Vidal‐Jordana, Andreu Vilaseca, Joaquín Castilló, Ingrid Galán, Luciana Midaglia, Carlos Nos, Breogan Rodríguez‐Acevedo, Ana Zabalza, Luca Bollo, Agustín Pappolla, René Carvajal, Neus Mongay‐Ochoa, Jordi Rio, Jaume Sastre‐Garriga, Manuel Comabella, Gesualdina Busiello, Sofia Sceppacuercia, Àlex Rovira, Xavier Montalban, Mar Tintoré, Cristina Auger, Álvaro Cobo‐Calvo   +29 more
wiley   +1 more source

Glycine is a transmitter in the human and chimpanzee cochlear nuclei

Frontiers in Neuroanatomy
IntroductionAuditory information is relayed from the cochlea via the eighth cranial nerve to the dorsal and ventral cochlear nuclei (DCN, VCN). The organization, neurochemistry and circuitry of the cochlear nuclei (CN) have been studied in many species ...
Joan S. Baizer, Chet C. Sherwood, Patrick R. Hof, James F. Baker, Sandra F. Witelson   +4 more
doaj   +1 more source

Why Can't Rodents Vomit? A Comparative Behavioral, Anatomical, and Physiological Study [PDF]

, 2013
The vomiting (emetic) reflex is documented in numerous mammalian species, including primates and carnivores, yet laboratory rats and mice appear to lack this response.
Andrews, PLR, Yates, Bill J., Andrews, PL, Yates, BJ, Allysa Nagy, Charles C Horn, Gathright, GR, Kimball, Bruce A., Wang, H, James Kaus, Horn, Charles C., Bill J. Yates, Charles C. Horn, Kaus, J, Hong Wang, Dienel, S, Bruce A. Kimball, Paul L. R. Andrews, Horn, CC, Dienel, Samuel, Kimball, BA, Nagy, A, Nagy, Allysa, Gordon R Gathright, Gathright, Gordon R., Andrews, Paul L. R., Bruce A Kimball, Kaus, James, Wang, Hong, Samuel Dienel, Paul L R Andrews, Bill J Yates, Gordon R. Gathright   +32 more
core   +2 more sources

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse, Takashi Matsukawa, Yumiko Nakamura, Kazuo Kakinuma, Shoko Ota, Ryo Hara, Saki Nakashima, Kaoru Ito, Yutaro Nakamori, Toshiyuki Kakumoto, Masashi Hamada, Shigenori Kanno, Kyoko Suzuki, Tatsushi Toda   +13 more
wiley   +1 more source

Characterization of direct Purkinje cell outputs to the brainstem

eLife
Purkinje cells (PCs) primarily project to cerebellar nuclei but also directly innervate the brainstem. Some PC-brainstem projections have been described previously, but most have not been thoroughly characterized.
Christopher H Chen, Zhiyi Yao, Shuting Wu, Wade G Regehr   +3 more
doaj   +1 more source

Spread of Oropouche Virus into the Central Nervous System in Mouse

Viruses, 2014
Oropouche virus (OROV) is an important cause of arboviral illness in Brazil and other Latin American countries, with most cases clinically manifested as acute febrile illness referred to as Oropouche fever, including myalgia, headache, arthralgia and ...
Rodrigo I. Santos, Lézio S. Bueno-Júnior, Rafael N. Ruggiero, Mariana F. Almeida, Maria L. Silva, Flávia E. Paula, Vani M. A. Correa, Eurico Arruda   +7 more
doaj   +1 more source

Brainstem fMRI

, 2020
The human brainstem plays important roles in maintaining basic vital functions. In comparison with brain functional magnetic resonance imaging (fMRI), only a few fMRI studies investigating the brainstem have been reported because of a number of technical
Zhi Lan, Zeping Lv, Yubo Fan, Pengxu Wei
core   +1 more source

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui, Jiayang Zhan, Wei Li, Tao Jin, Dan He, Daishi Tian, Zhijun Li, Jing Lin, Yue Li, Hongyu Zhou, Bitao Bu   +10 more
wiley   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source