Results 101 to 110 of about 290,088 (286)
Quantum cosmology with big-brake singularity
, 2007 We investigate a cosmological model with a big-brake singularity in the future: while the first time derivative of the scale factor goes to zero, its second time derivative tends to minus infinity.
A. Ashtekar +10 more
core +1 more source
Advanced Science, EarlyView.A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang +7 more
wiley +1 more source
, 2013 When W. T. Stead died on the Titanic he was the most famous Englishman on board. A mass of contradictions and a crucial figure in the history of the British press, Stead was a towering presence in the cultural life of late-Victorian and Edwardian society.
Brake, Laurel, Mussell, James
core
Advanced Science, EarlyView.We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun +13 more
wiley +1 more source
The mechanism here described belongs to the class of dynamometer brake in which the motive power is transformed into heat in the brake itself. This mechanism was invented by the writer for the purpose of measuring forces in which the two factors, torque ...
Segre, Marco
core +1 more source
Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems
Advanced Science, EarlyView.A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller +9 more
wiley +1 more source
FluidsThis work focused on the development of a complete laboratory procedure for the rheological characterization of magnetorheological fluids (MRFs) by combining information gained from the literature and practical work performed in the laboratory.
Guglielmo Peruzzi +5 more
doaj +1 more source
Advanced Science, EarlyView.Confinement by nanoscale covalent organic frameworks reinforces hydrogels, imparting exceptional mechanical strength and ionic conductivity for high‐performance electrolyte applications. ABSTRACT Hydrogels are widely applied in various fields, including energy storage and flexible electronics. However, their mechanical properties often fail to meet the
Peiyao Yan +15 more
wiley +1 more source
Analysis of air flow and heat dissipation from a high performance passenger car front brake rotor [PDF]
, 2006 The increasing demand from the consumer for higher levels of refinement from their passenger vehicles has put considerable pressure on the automotive industry to produce ever quieter cars. In order to prevent the occurrence of many forms of brake noise,
Fieldhouse, John D. +2 more
core
ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology
Advanced Science, EarlyView.This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li +25 more
wiley +1 more source