Results 91 to 100 of about 292,101 (301)
Load proportional safety brake [PDF]
This brake is a self-energizing mechanical friction brake and is intended for use in a rotary drive system. It incorporates a torque sensor which cuts power to the power unit on any overload condition.
Cacciola, M. J.
core +1 more source
Quantification and description of braking during mountain biking using a novel brake power meter : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Sport & Exercise at Massey University, Palmerston North, New Zealand [PDF]
, 2017 Olympic format cross country mountain biking is both physically and technically demanding. The demands of this cycling genre are in contrast to road cycling because of the demanding off-road terrain.
Miller, Matthew Curtis
core
Advanced Science, EarlyView.This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng +13 more
wiley +1 more source
Advanced Science, EarlyView.Plastin‐2 (PLS2) is identified as a dual‐function receptor on DCs that mediates both nanoparticle uptake and immunomodulation. A nanobody‐LNP platform is engineered to integrate antigen delivery with relicensing DCs. The therapeutic strategy elicits potent anti‐tumor T cell responses and leads to significant inhibition of established tumors in vivo ...
Shugang Qin +9 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv +8 more
wiley +1 more source
Angewandte Chemie, EarlyView.MOF‐CAPodes are introduced by pairing various p‐MOFs with an n‐MOF as electrode materials in a battery‐like assembly. The devices achieve high figures of merit (RRI = 23.5; RRII = 94.4%) and perform excellently in prototypical logic gates (AND, OR) highlighting a new direction for ionological systems based on electroactive MOFs.
Tim Engelhardt +9 more
wiley +2 more sources
Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease
Advanced Science, EarlyView.This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang +15 more
wiley +1 more source
A PERSPECTIVE ON THE FINANCIAL SITUATION IN AGRICULTURE [PDF]
My purpose in this presentation is to give an overview or perspective on the financial situation in U.S. agriculture. Since descriptions of the situation are generally available (Easterbrook, J.
Brake, John R.
core +1 more source
Advanced Science, EarlyView.Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong +21 more
wiley +1 more source
Brake lock mechanism for the two axis pointing system [PDF]
Six months prior to shipment of the Broadband X-ray Telescope to the Kennedy Space Center for flight aboard the Space Shuttle Columbia, a major system failure occurred.
Clark, Mike, Mignosa, Larry, Posey, Alan
core +1 more source