Results 101 to 110 of about 292,101 (301)

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

open access: yesAdvanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li   +8 more
wiley   +1 more source

Rheological Characterization of Magnetorheological Fluids for Brake Applications: An Experimental Procedure

open access: yesFluids
This work focused on the development of a complete laboratory procedure for the rheological characterization of magnetorheological fluids (MRFs) by combining information gained from the literature and practical work performed in the laboratory.
Guglielmo Peruzzi   +5 more
doaj   +1 more source

Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes

open access: yesAdvanced Science, EarlyView.
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang   +8 more
wiley   +1 more source

Brake tests to evaluate the human behaviour at different brake pedal characteristics [PDF]

open access: yes
-Brake-by-wire represents the replacement of traditional brake components such as pumps, hoses, fluids, brake boosters, and tandem master cylinders by electronic sensors and actuators.
Ball, Andrew   +4 more
core  

Light‑Driven Propulsion of Graphene Aerogels in Microgravity

open access: yesAdvanced Science, EarlyView.
Ultralight graphene aerogels convert laser light into thrust. Parabolic‐flight experiments directly compare their motion in microgravity and at 1 g, revealing order‐of‐magnitude enhancements in distance, velocity, and transient thrust when weight and friction are removed (∼50 times enhancement).
Omnia Khattab   +10 more
wiley   +1 more source

A New Dynamometer Brake [PDF]

open access: yes
The mechanism here described belongs to the class of dynamometer brake in which the motive power is transformed into heat in the brake itself. This mechanism was invented by the writer for the purpose of measuring forces in which the two factors, torque ...
Segre, Marco
core   +1 more source

Self‐Powered Bearing Sensing and Real‐Time Fault Diagnosis Enabled by Non‐Invasive Triboelectric Sensors and Edge AI Acceleration

open access: yesAdvanced Science, EarlyView.
This study achieves the synergistic integration of self‐powered sensing and edge AI acceleration to establish a real‐time fault diagnosis system. The proposed TENG‐based self‐powered bearing sensor (NSE‐TBS) and FPGA‐accelerated edge AI framework fundamentally break through the inherent limitations of conventional monitoring systems, including complex ...
Kehui Zhu   +7 more
wiley   +1 more source

Analysis on the Performance of New Mountain Gear Rail Train Brake

open access: yesChengshi guidao jiaotong yanjiu
Objective The maximum slope of the mountain gear rail line can reach 250‰. As the sliding force generated by the component of the gravity is much greater than the maximum friction force between wheel and rail, relying solely on the conventional wheel and
CUI Yin   +4 more
doaj   +1 more source

Design oriented simulation of contact-friction instabilities in application to realistic brake assemblies [PDF]

open access: yes, 2010
This paper presents advances in non-linear simulations for systems with contact-friction, with an application to brake squeal. A method is proposed to orient component structural modifications from brake assembly simulations in the frequency and time ...
BALMES, Etienne   +3 more
core   +3 more sources

Automation of Surgical Workflow Recognition: Unveiling the Surgical Instrument Kinematics that Underly Robot‐Assisted Prostatectomy Procedures

open access: yesAdvanced Intelligent Discovery, EarlyView.
Automated procedural analysis is recognized as one of the major game changers for robotic surgery. Meaning digital analysis needs to replace the manual assessments that set todays standard. Mechanical robotic‐instrument tracking enables the derivation of quantitative kinematic metrics that support behavior‐based workflow segmentation into distinct ...
Kateryna Pirkovets   +4 more
wiley   +1 more source

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