Results 81 to 90 of about 292,101 (301)
Friction material (metal reinforcement) analysis of brake pad for light rail train system [PDF]
, 2016 Brake friction material is very important in braking system where they convert kinetic energy of moving vehicles to thermal energy by friction during braking process. The purpose of this research is to determine the optimal friction materials composition
Abdul Rahman, Abdul Rashid
core
Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Advanced Science, EarlyView.Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
Механика машин, механизмов и материалов, 2016 Most often meeting reason of failure while in service frictional brakes and frictional knots in caterpillar and wheel cars is deformability of frictional disks. Deformability of disks leads to indistinct inclusion and deenergizing of the frictional knot,
Vladimir E. Antonyuk
doaj
Method of combating fatigue destruction of steel structures of mine hoisting machines
Metalurgija, 2020 The article presents the information of the identified defects of fatigue failure of steel structures of the brake mechanism of mine cable hoisting machines used to transport metallurgical coke from the mine to the surface.
A. D. Mekhtiyev +5 more
doaj
Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems
Advanced Science, EarlyView.A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller +9 more
wiley +1 more source
Tradeoff between Smoother and Sooner "Little Rip"
, 2013 There exists dark energy models that predict the occurrence of "little rip". At the point of little rip the Hubble rate and its cosmic time derivative approach infinity, which is quite similar to the big rip singularity except that the former happens at ...
Bouhmadi-Lopez, Mariam +2 more
core +1 more source
Advanced Science, EarlyView.Confinement by nanoscale covalent organic frameworks reinforces hydrogels, imparting exceptional mechanical strength and ionic conductivity for high‐performance electrolyte applications. ABSTRACT Hydrogels are widely applied in various fields, including energy storage and flexible electronics. However, their mechanical properties often fail to meet the
Peiyao Yan +15 more
wiley +1 more source
ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology
Advanced Science, EarlyView.This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li +25 more
wiley +1 more source
Hydraulic brake safety valve [PDF]
, 1970 Safety device, consisting of three separate fluid chambers, insures that two wheels of a brake system continue to function if a failure ...
Hobson, Z. A.
core +1 more source
Advanced Science, EarlyView.After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang +19 more
wiley +1 more source