Results 71 to 80 of about 80,558 (315)

Borneomyia Brake [PDF]

open access: yes, 2004
Borneomyia Brake, n. gen. Genus nov 1, in Brake 2000. Type species: Borneomyia tigra Brake, n. sp., by present designation. Description: Body wholly subshiny, only mesonotum slightly more shiny. Body usually yellow with brown stripes.
Brake, Irina
core   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

open access: yesAdvanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee   +11 more
wiley   +1 more source

FIGURES 1 – 4. Borneomyia tigra Brake n in Borneomyia, a new genus and two new species of Milichiidae (Diptera, Schizophora) [PDF]

open access: yes, 2004
FIGURES 1 – 4. Borneomyia tigra Brake n. sp., male (from Brake 2000). 1: Head, frontal view; 2 – 3: Midfemur with femoral organ, anterodorsal view; 4: Basitarsomere of hindleg, anteroventral view.
Brake, Irina, Brake, Irina (5208799)
core   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

open access: yesAdvanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng   +13 more
wiley   +1 more source

Features of the Design and Manufacturing Techniques of Frictional Disks of Caterpillar and Wheel Cars

open access: yesМеханика машин, механизмов и материалов, 2016
Most often meeting reason of failure while in service frictional brakes and frictional knots in caterpillar and wheel cars is deformability of frictional disks. Deformability of disks leads to indistinct inclusion and deenergizing of the frictional knot,
Vladimir E. Antonyuk
doaj  

Improving the method of controlling the stress-strain state of steel structures of electromechanical systems

open access: yesMetalurgija, 2023
The article presents the results of improving the method of controlling the stress-strain state of steel structures of mine hoisting machines, which can be attributed to electromechanical systems.
A. B. Zhantlessova   +7 more
doaj  

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

open access: yesAdvanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang   +15 more
wiley   +1 more source

High-speed-braking performance of rubber brake filled with RB ceramics particles under rain conditions

open access: yesNihon Kikai Gakkai ronbunshu, 2019
We developed a brake shoe made of a fluorine-contained rubber (FKM) compound filled with rice bran ceramics (RBC) particles for a caliper brake of bicycle and evaluated the braking performance and tribological properties on the wet condition from high ...
Kei SHIBATA   +4 more
doaj   +1 more source

Material characterization and unconventional machining on synthesized Niobium metal matrix

open access: yesMaterials Research Express, 2020
The Purpose of this work is to develop a niobium based metal matrix alloy through sintering based powder metallurgy technique. The 2, 4 and 6 weight percentage of Titanium Carbide (TiC) is added to the alloy. Various material properties such as hardness,
C Sivakandhan   +6 more
doaj   +1 more source

Braking Pattern Impact on Brake Fade in an Automobile Brake System

open access: yesJournal of Engineering Sciences, 2019
The importance of brake systems in automobiles cannot be overemphasized. Brakes are used in speed control of vehicles and do so by the conversion of kinetic energy into thermal energy. Better stopping performance has favored the disc brake system over the drum brake system and has found wide application in high-performance vehicles.
openaire   +3 more sources

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