Results 81 to 90 of about 290,088 (286)

Load proportional safety brake [PDF]

open access: yes
This brake is a self-energizing mechanical friction brake and is intended for use in a rotary drive system. It incorporates a torque sensor which cuts power to the power unit on any overload condition.
Cacciola, M. J.
core   +1 more source

Who do they think they're talking to? framings of the audience by social media users [PDF]

open access: yes, 2012
This paper examines the understandings and meanings of personal information sharing online using a predominantly symbolic interactionist analytic perspective and focusing on writers’ conceptions of their relationships with their audiences. It draws on an
Brake, David R.
core  

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

open access: yesAdvanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang   +10 more
wiley   +1 more source

Use of reinforcing elements to improve fatigue strength of steel structures of mine hoisting machines (MHM)

open access: yesMetalurgija, 2020
The article discusses the issues of fatigue fracture of steel structures and the method of increasing their strength through the use of reinforcing elements.
A. D. Mekhtiyev   +5 more
doaj  

Behavior of aircraft antiskid braking systems on dry and wet runway surfaces: Hydromechanically controlled system [PDF]

open access: yes
The investigation utilized one main gear wheel, brake, and tire assembly of a McDonnell Douglas DC-9 series 10 airplane. The landing-gear strut was replaced by a dynamometer.
Smith, E. G.   +2 more
core   +1 more source

Tradeoff between Smoother and Sooner "Little Rip"

open access: yes, 2013
There exists dark energy models that predict the occurrence of "little rip". At the point of little rip the Hubble rate and its cosmic time derivative approach infinity, which is quite similar to the big rip singularity except that the former happens at ...
Bouhmadi-Lopez, Mariam   +2 more
core   +1 more source

PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu   +11 more
wiley   +1 more source

Features of the Design and Manufacturing Techniques of Frictional Disks of Caterpillar and Wheel Cars

open access: yesМеханика машин, механизмов и материалов, 2016
Most often meeting reason of failure while in service frictional brakes and frictional knots in caterpillar and wheel cars is deformability of frictional disks. Deformability of disks leads to indistinct inclusion and deenergizing of the frictional knot,
Vladimir E. Antonyuk
doaj  

Method of combating fatigue destruction of steel structures of mine hoisting machines

open access: yesMetalurgija, 2020
The article presents the information of the identified defects of fatigue failure of steel structures of the brake mechanism of mine cable hoisting machines used to transport metallurgical coke from the mine to the surface.
A. D. Mekhtiyev   +5 more
doaj  

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