Results 51 to 60 of about 19,940 (234)

Effects of Titanate on Brake Wear Particle Emission Using a Brake Material Friction Test Dynamometer

Lubricants
We investigated the effect of lepidocrocite-type layered titanate, which is compounded in brake pads, to reduce brake particle emissions. The dust reduction effect of titanate was evaluated using a small-scale inertial brake material friction test ...
Emiko Daimon, Yasuhito Ito
doaj   +1 more source

Penyelidikan Kekuatan Tekan dan Laju Keausan Komposit dengan Filler Palm Slag sebagai Bahan Penyusun Kanvas Rem Sepeda Motor [PDF]

, 2014
Palm slag as waste burning of palm shells and bunches for boiler fuel is available in abundance. Availability of abundant is potential to be developed as a filler of brake composite. The using of palm slag as filler composite non-asbestos brake pads have
Badri, M. (Muftil), Riduan, J. P. (Jon), Yohanes, Y. (Yohanes)   +2 more
core  

How to play a disc brake [PDF]

, 1999
We consider a gyroscopic system under the action of small dissipative and non-conservative positional forces, which has its origin in the models of rotating bodies of revolution being in frictional contact.
Dent, WRF, Friberg, P, Greaves, Jane Sophia, Holland, WS   +3 more
core   +3 more sources

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Molecular brake pad hypothesis: pulling off the brakes for emotional memory [PDF]

Reviews in the Neurosciences, 2012
Under basal conditions histone deacetylases(HDACs) and their associated co-repressor complexes serve as molecular 'brake pads' to prevent the gene expression required for long-term memory formation. Following a learning event, HDACs and their co-repressor complexes are removed from a subset of specific gene promoters, allowing the histone acetylation ...
Annie, Vogel-Ciernia, Marcelo A, Wood
openaire   +2 more sources

Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease

Advanced Science, EarlyView.
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang, Yuting Liu, Shufan Jiang, Zilin Fang, Mengda Jiang, Xiaofeng Tao, Tianyi Zhu, Jipeng Li, Sijie Fang, Xuefei Song, Yinwei Li, Jing Sun, Chuanjun Tong, Zhengrun Gao, Huifang Zhou, Xianqun Fan   +15 more
wiley   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Benchmarking Signorini and exponential contact laws for an industrial train brake squeal application [PDF]

, 2012
Contact representation of structure interactions for finite element models is nowadays of great interest in the industry. Two contact modellig strategies exist in the literature, either based on a perfect contact with no interpenetration of structures at
BALMES, Etienne, CHIELLO, Olivier, LORANG, Xavier, VERMOT DES ROCHES, Guillaume   +3 more
core   +3 more sources

The UT 19-channel DC SQUID based neuromagnetometer [PDF]

, 1991
A l9-channel DC SQUID based neuromagnetometer is under construction at the University of Twente (UT). Except for the cryostat all elements of the system are developed at the UT.
Ancum, G.K. van, Brake, H.J.M. ter, Flokstra, J., Jaszczuk, W., Martinez, A., Rogalla, H., Stammis, R.   +6 more
core   +4 more sources