Results 71 to 80 of about 42,708 (298)

Oncolytic Probiotics with Molecular Pili for Solid Tumor Therapy

Advanced Science, EarlyView.
This study identifies Lactobacillus rhamnosus as an intrinsic oncolytic agent that triggers tumor metabolic collapse via calcium‐dependent ROS bursts. By chemically anchoring collagen‐targeting “molecular pili” to the bacterial surface, the engineered non‐transgenic probiotic (LR@MP) achieves targeted colonization and potent solid tumor suppression ...
Haodong Ge, Chengsheng Ding, Xiao Yang, Si Gao, Changjie Yang, Yuchen Hou, Hongye Wang, Linke Bian, Hao Zhong, Yifan Qu, Luyang Zhang, Junjun Ma, Zhengwei Cai, Wenguo Cui, Minhua Zheng   +14 more
wiley   +1 more source

Mass loss in main-sequence B stars

, 2014
We calculate radiatively driven wind models of main-sequence B stars and provide the wind mass-loss rates and terminal velocities. The main-sequence mass-loss rate strongly depends on the stellar effective temperature.
Krticka, Jiri
core   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

USING COUPLING WEIGHTS AND RATIONAL DISTRIBUTION OF BRAKE FORCES BETWEEN THE AXLES OF WHEELED VEHICLES [PDF]

Avtomobilʹnyj Transport (Harʹkov), 2011
The dependence of the coefficient of coupling weight-axle vehicles under braking and a ra-tional distribution coefficient of braking force to the front axle on the condition of maximum coupling weight.
M. Kholodov, M. Podrigalo
doaj  

Mitophagy and Ubiquitination Coordinate Context‐Specific Mitochondrial Quality Control and EMT/MET Plasticity to Drive Cancer Cell Invasion

Advanced Science, EarlyView.
Metastatic invasion emerges when tumor‐intrinsic programs and microenvironmental forces converge on mitochondrial quality control. A context‐stratified framework links mtROS, mtDNA integrity, mechanics and nutrient/oxygen cues to fission–fusion remodeling, mtUPR and mitophagy.
Bin‐Hsu Mao, Bo‐Kai Su, Ying‐Jan Wang, Ting‐Yuan Tu   +3 more
wiley   +1 more source

IDEAL BRAKE FORCE DISTRIBUTION BETWEEN THE AXLES OF THE TWO-AXLE VEHICLE SERVICE BRAKE APPLICATIONS [PDF]

Avtomobilʹnyj Transport (Harʹkov), 2015
The obtained analytical expressions allow us to evaluate the stability of two-axle vehicles at various slowdowns. An analytical expression for calculating the ideal according to condition stability ensuring of a two-axle vehicle at service brake ...
M. Podryhalo, A. Turenko
doaj  

Development of a Cooperative Braking System for Front-Wheel Drive Electric Vehicles

Energies, 2018
Most electric vehicles adopt cooperative braking systems that can blend friction braking torque with regenerative braking torque to achieve higher energy efficiency while maintaining a certain braking performance and driving safety.
Di Zhao, Liang Chu, Nan Xu, Chengwei Sun, Yanwu Xu   +4 more
doaj   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Analysis of the Braking Performance of the Hydraulic Retarder in Mining Dump Truck based on AMESim

Jixie chuandong, 2016
The hydrodynamic retarder is one of the important auxiliary braking system in mining dump truck,which has an important influence on the braking force distribution and braking performance of the vehicle.
Deng Lin
doaj  

Composite Braking Control Strategy for Electromechanical-Hydraulic Vehicles

CSEE Journal of Power and Energy Systems
Short driving ranges and low braking energy recovery efficiencies are two recognized technical bottlenecks to be overcome in electric vehicles. In this paper, a novel electromechanical-hydraulic coupling system is proposed and integrated as a powertrain ...
Zewen Meng, Jichao Hong, Hongxin Zhang, Tiezhu Zhang, Xiaoming Xu, Qinghai Zhao, Jian Yang   +6 more
doaj   +1 more source